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PF-03394197

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842823

Background: PF-03394197 is potent and selective Janus kinase (JAK) inhibitor. It inhibits JAK family members with an IC?? of 10-99 nM being most potent against JAK1 (IC?? = 10 nM). PF-03394197 does not inhibit a panel of 38 non-JAK kinases (IC?? >1 uM).… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-03394197, Biochemical
Full Product Name
PF-03394197
Product Synonym Names
N-Methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide; Oclacitinib
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
337.44
CAS Number
1208319-26-9
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
44631938
Solubility/Reconstitution Instructions
DMSO (>30 mg/ml)
SMILES
CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3
InChi
InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)
InChi Key
HJWLJNBZVZDLAQ-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for PF-03394197 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; JAK InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; JAK InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Biochem

Structure of PF-03394197 biochemical

Pf-03394197 Biochemical – Cat# MBS842823

Other Notes

Small volumes of PF-03394197 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-03394197 purchase

MBS842823 is a biochemical targeting PF-03394197.
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