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PXD101

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842927

Background: A potent histone deacetylase (HDAC) activity inhibitor. It inhibits HDAC activity in HeLa cell extracts with an IC?? of 27 nM. Belinostat significantly increases acetylation of histones H3 and H4 and potently inhibits the growth of prostate cancer… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PXD101, Biochemical
Full Product Name
PXD101
Product Gene Name
PXD101 biochemical
Product Synonym Names
(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide; Belinostat
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
318.35
CAS Number
414864-00-9
Structure Available?
Yes
Cell-Permeable?
Yes
PubChem CID
6918638
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO
InChi
InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChi Key
NCNRHFGMJRPRSK-MDZDMXLPSA-N
Handling
Protect from air and light

Product Categories/Family for PXD101 biochemical

Enzyme Inhibitors; Histone Deacetylase (HDAC) Inhibitors and Biochemicals; Enzyme Inhibitors; Histone Deacetylase (HDAC) Inhibitors and Epigenetics; Eraser Enzymes; Histone Deacetylases; HDAC Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of PXD101 biochemical

PXD101 Biochemical – Cat# MBS842927

Other Notes

Small volumes of PXD101 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PXD101 purchase

MBS842927 is a biochemical targeting PXD101.
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