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Sphingosine Kinase Inhibitor, SKI-II

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843295

Background: Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 uM, with no inhibition against ERK2, PI3-kinase, or PKCalpha at… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Sphingosine Kinase Inhibitor, SKI-II, Biochemical
Full Product Name
Sphingosine Kinase Inhibitor, SKI-II
Product Synonym Names
4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
Form/Format
Appearance: Off-white solid
Purity/Purification
>=90% by NMR
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
302.78
CAS Number
312636-16-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00733553
PubChem CID
753704
Solubility/Reconstitution Instructions
DMSO (100 mM)
SMILES
C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
InChi
InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)
InChi Key
ZFGXZJKLOFCECI-UHFFFAOYSA-N
Handling
Protect from air and light

Other Notes

Small volumes of Sphingosine Kinase Inhibitor, SKI-II biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS843295 is a biochemical targeting Sphingosine Kinase Inhibitor, SKI-II.
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