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Cyclophilin G (PPIG) Human Recombinant Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844420

Background: Peptidyl-prolyl cis-trans isomerase G (PPIG), also known as Cyclophilin G, is a member of peptidylprolyl cis-trans isomerase family (PPIases). This protein catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cyclophilin G (PPIG), Active Protein
Full Product Name
Human Recombinant Cyclophilin G
Product Gene Name
Product Synonym Names
Peptidyl-prolyl cis-trans isomerase G; PPIase G; Rotamase G; PPIG; peptidylprolyl isomerase G; Peptidyl-prolyl isomerase G; Rotamase G; Clk-associating RS-cyclophilin; CARS-cyclophilin; CARS-Cyp; SR-cyclophilin; SR-cyp; SRcyp; CASP10; CYP; MGC133241.; Human Recombinant Cyclophilin G
Sequence
MGSSHHHHHH SSGLVPRGSH MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCG
Host
E Coli
Form/Format
1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, and 10% glycerol.
Appearance: Liquid
Purity/Purification
>=95%
Concentration
1 mg/ml (lot specific)
Preparation and Storage
At -80 degree C
Shelf Life: 12 months
Molecular Weight
21.6 kDa
OMIM
606093
3D Structure
ModBase 3D Structure for Q13427
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Specific activity is > 200 nmoles/min/mg.
Unit Definition
Specific activity and is defined as the amount of enzyme that cleaves 1 umole of Suc-AAFP-pNA per minute at 25 degree C in Tris HCl pH 8.0 using chymotrypsin.
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for PPIG active protein
SDS-PAGE

Testing Data of PPIG active protein

Human Recombinant PPIG Active Protein – Cat# MBS844420

Other Notes

Small volumes of PPIG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIG purchase

MBS844420 is an active protein targeting PPIG. Also known as Human Recombinant Cyclophilin G. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase G
NCBI Official Synonym Full Names
peptidylprolyl isomerase G (cyclophilin G)
NCBI Official Symbol
PPIG
NCBI Official Synonym Symbols
CYP; SRCyp; SCAF10; CARS-Cyp
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase G
UniProt Synonym Protein Names
CASP10; Clk-associating RS-cyclophilin; CARS-Cyp; CARS-cyclophilin; SR-cyclophilin; SR-cyp; SRcyp; Cyclophilin G; Rotamase G
UniProt Gene Name
PPIG
UniProt Synonym Gene Names
PPIase G; Peptidyl-prolyl isomerase G; CARS-Cyp; CARS-cyclophilin; SR-cyclophilin; SR-cyp; SRcyp
UniProt Entry Name
PPIG_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase G

UniProt Comments for PPIG

PPIG: an ubiquitous peptidyl-prolyl cis/trans isomerase. Distributed in nuclear speckles, which are rich in splicing factors. Colocalizes with the splicing factor SFRS2. A component of splicing factor complexes that bind the phosphorylated C-terminal domain (CTD) of RNA polymerase II. Interacts with CLK1 and PNN. Two splice variant isoforms of the human protein have been described.

Protein type: Cyclophilin; EC 5.2.1.8; Isomerase

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: nucleoplasm; nuclear matrix; cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding

Biological Process: protein peptidyl-prolyl isomerization; protein folding; RNA splicing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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