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PPIL3 Human Recombinant Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844790

Background: Peptidyl-prolyl cis-trans isomerase-like 3 in humans is encoded by the PPIL3 gene. This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PPIL3, Active Protein
Full Product Name
Human Recombinant PPIL3
Product Gene Name
Product Synonym Names
Peptidyl-prolyl cis-trans isomerase-like 3 isoform PPIL3b; CYPJ.; Human Recombinant PPIL3
Sequence
MGSSHHHHHH SSGLVPRGSH MSVTLHTDVG DIKIEVFCER TPKTCENFLA LCASNYYNGC IFHRNIKGFM VQTGDPTGTG RGGNSIWGKK FEDEYSEYLK HNVRGVVSMA NNGPNTNGSQ FFITYGKQPH LDMKYTVFGK VIDGLETLDE LEKLPVNEKT YRPLNDVHIK DITIHANPFA Q
Host
E Coli
Form/Format
1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, and 1 mM DTT.
Appearance: Liquid
Purity/Purification
>=90%
Concentration
1 mg/ml (lot specific)
Preparation and Storage
At -80 degree C
Shelf Life: 12 months
Molecular Weight
20.3 kDa
OMIM
615811
3D Structure
ModBase 3D Structure for Q9H2H8
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Specific activity is > 280 nmoles/min/mg
Unit Definition
Specific activity is defined as the amount of enzyme that cleaves 1 umole of suc-AAFP-pNA per minute at 25 degree C in Tris-HCl pH 8.0 using chymotrypsin.
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for PPIL3 active protein
SDS-PAGE

Testing Data of PPIL3 active protein

Human Recombinant PPIL3 Active Protein – Cat# MBS844790

Other Notes

Small volumes of PPIL3 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIL3 purchase

MBS844790 is an active protein targeting PPIL3. Also known as Human Recombinant PPIL3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase-like 3 isoform PPIL3a
NCBI Official Synonym Full Names
peptidylprolyl isomerase (cyclophilin)-like 3
NCBI Official Symbol
PPIL3
NCBI Official Synonym Symbols
CYPJ
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase-like 3
UniProt Synonym Protein Names
Cyclophilin J; CyPJ; Cyclophilin-like protein PPIL3; Rotamase PPIL3
UniProt Gene Name
PPIL3
UniProt Synonym Gene Names
PPIase; CyPJ
UniProt Entry Name
PPIL3_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase-like 3

NCBI Summary for PPIL3

This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
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UniProt Comments for PPIL3

PPIL3: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cyclophilin; Isomerase; Spliceosome; EC 5.2.1.8

Chromosomal Location of Human Ortholog: 2q33.1

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity

Biological Process: nuclear mRNA splicing, via spliceosome; protein peptidyl-prolyl isomerization; protein folding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PPIL3 active protein

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with PPIL3 and Carcinoma
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