SDC1 Recombinant Protein – Cat# MBS8122886

Syndecan-1/CD138 (SDC1) Recombinant Protein

Name: SDC1 Recombinant Protein; Syndecan-1/CD138; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS8122886
Price: 415 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8122886

Background: Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has… More details

$415 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Syndecan-1/CD138 (SDC1), Recombinant Protein

Full Product Name

Syndecan-1/CD138 Protein, Mouse, Recombinant (His Tag)

Product Gene Name

SDC1 recombinant protein

Product Synonym Names

Mouse Syndecan-1/SDC1/CD138 Protein (His Tag); AA408134 Protein, Mouse; AA409076 Protein, Mouse; CD138 Protein, Mouse; Sstn Protein, Mouse; syn-1 Protein, Mouse; Synd Protein, Mouse; Synd1 Protein, Mouse; syndecan 1

Host

HEK293 Cells

Form/Format

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose 5% mannitol and 0.01% Tween80.

Purity/Purification

>80% as determined by SDS-PAGE

Preparation and Storage

Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

3D Structure

ModBase 3D Structure for P18828

Source

Mouse

Endotoxin

<1.0EU per ug of the protein as determined by the LAL method

Predicted N Terminal

Gln 17

Tag

His-Tag

Molecular Mass

The secreted recombinant mouse SDC1 comprises 246 amino acids and has a calculated molecular mass of 26 kDa. As a result of different glycosylation, the apparent molecular mass of rm SDC1 is approximately 45-60 kDa in SDS-PAGE under reducing conditions.

Product References and Citations for SDC1 recombinant protein

Inki P, et al. (1996) The role of syndecan-1 in malignancies. Ann Med. 28(1): 63-7.Subramanian SV, et al. (1997) Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation. J Biol Chem. 272(23): 14713-20.Park PW, et al. (2001) Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence. Nature. 411(6833): 98-102.

Other Notes

Small volumes of SDC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SDC1 purchase

MBS8122886 is a recombinant protein targeting SDC1. Also known as Syndecan-1/CD138 Protein, Mouse, Recombinant (His Tag). Host: HEK293 Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for SDC1. It may not necessarily be applicable to this product.

NCBI GI #

6755438

NCBI GeneID

20969

NCBI Accession #

NP_035649.1

UniProt Primary Accession #

P18828

UniProt Secondary Accession #

Q62278; Q9WVD2

UniProt Related Accession #

P18828

GenBank Nucleotide #

NM_011519.2

NCBI Official Full Name

syndecan-1

NCBI Official Synonym Full Names

syndecan 1

NCBI Official Symbol

Sdc1

NCBI Official Synonym Symbols

Sstn; Synd; CD138; Synd1; syn-1; AA408134; AA409076

UniProt Protein Name

Syndecan-1

UniProt Synonym Protein Names

CD_antigen: CD138

Protein Family

COMPASS component

UniProt Gene Name

Sdc1

UniProt Synonym Gene Names

Synd-1; Synd1; SYND1

NCBI Protein Information

syndecan-1

UniProt Comments for SDC1

syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family.

Protein type: Extracellular matrix; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12 A1.1|12 3.94 cM

Cellular Component: cell surface; cytoplasm; external side of plasma membrane; focal adhesion; protein complex

Molecular Function: glycoprotein binding; protein C-terminus binding

Biological Process: cell migration; inflammatory response; myoblast development; Wnt receptor signaling pathway through beta-catenin

Research Articles on SDC1

1. This study indicates that, while syndecan-1 is important for providing a barrier to acute S. aureus infection in PD, it does not affect peritoneal fibrosis and angiogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SDC1 recombinant protein

Reference Product	PubMed Publications
Sdc4 recombinant protein	>66 publications with SDC1 and Sdc4
Fgf2 recombinant protein	>54 publications with SDC1 and Fgf2
Sdc2 recombinant protein	>34 publications with SDC1 and Sdc2
Sdc3 recombinant protein	>17 publications with SDC1 and Sdc3
Hpse recombinant protein	>4 publications with SDC1 and Hpse
Gpc1 recombinant protein	>3 publications with SDC1 and Gpc1
Hspg2 recombinant protein	>1 publications with SDC1 and Hspg2
Hpse2 recombinant protein	>1 publications with SDC1 and Hpse2

Pathways associated with SDC1 recombinant protein

Products by Pathway	Pathway Diagram
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies	A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
HS-GAG Biosynthesis Pathway antibodies	HS-GAG Biosynthesis Pathway Diagram

Diseases associated with SDC1 recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>210 publications with SDC1 and Cardiovascular Diseases
Inflammation Antibodies	>82 publications with SDC1 and Inflammation
Adenocarcinoma Antibodies	>61 publications with SDC1 and Adenocarcinoma
Breast Neoplasms Antibodies	>41 publications with SDC1 and Breast Neoplasms
Necrosis Antibodies	>38 publications with SDC1 and Necrosis
Nervous System Diseases Antibodies	>30 publications with SDC1 and Nervous System Diseases
Fibrosis Antibodies	>26 publications with SDC1 and Fibrosis
Neoplasms, Experimental Antibodies	>25 publications with SDC1 and Neoplasms, Experimental
Kidney Diseases Antibodies	>23 publications with SDC1 and Kidney Diseases
Lung Neoplasms Antibodies	>21 publications with SDC1 and Lung Neoplasms

Organs/Tissues associated with SDC1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>178 publications with SDC1 and Bone
Bone Marrow Antibodies	>153 publications with SDC1 and Bone Marrow
Skin Antibodies	>47 publications with SDC1 and Skin
Liver Antibodies	>43 publications with SDC1 and Liver
Lung Antibodies	>42 publications with SDC1 and Lung
Kidney Antibodies	>40 publications with SDC1 and Kidney
Muscle Antibodies	>32 publications with SDC1 and Muscle
Intestine Antibodies	>31 publications with SDC1 and Intestine
Connective Tissue Antibodies	>23 publications with SDC1 and Connective Tissue
Bladder Antibodies	>23 publications with SDC1 and Bladder