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AHU-377 (4- ( ( (2S)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845702

AHU-377 is a prodrug that is activated in vivo by esterases to form an active compound LBQ657 which acts as a potent and selective neprilysin inhibitor. Neprilysin is a protease responsible for the degradation of atrial and brain natriuretic peptides.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AHU-377, Biochemical
Full Product Name
AHU-377
Product Gene Name
AHU-377 biochemical
Product Synonym Names
4- ( ( (2S; 4R)-1- ([1; 1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl) amino)-4-oxobutanoate; Sacubitril
Form/Format
Light yellow oil
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
411.49
Salt Form
No
CAS Number
149709-62-6
Cell-Permeable
Yes
Reconstitution
DMSO (>5 mg/ml)
SMILES
CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
InChi
InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m1/s1
InChi Key
PYNXFZCZUAOOQC-UTKZUKDTSA-N

Structure of AHU-377 biochemical

AHU-377 4- ( ( (2S Biochemical – Cat# MBS845702

Other Notes

Small volumes of AHU-377 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AHU-377 purchase

MBS845702 is a biochemical targeting AHU-377.
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