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LLY-507

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846255

LLY-507 is a potent; cell-permeable; small molecule inhibitor of SMYD2 (IC50 = 15 nM); a lysine N-methyltransferase. It has been shown to inhibit p53 lysine monomethylation in KYSE-150 esophageal squamous cell carcinoma cells stably expressing SMYD2 with an… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LLY-507, Biochemical
Full Product Name
LLY-507
Product Gene Name
Product Synonym Names
5-Cyano-2'-[4-[2- (3-methyl-1H-indol-1-yl) ethyl]-1-piperazinyl]-N-[3- (1-pyrrolidinyl) propyl]-[1; 1'-biphenyl]-3-carboxamide
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
574.8
Salt Form
No
CAS Number
1793053-37-8
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
O=C(C1=CC(C2=CC=CC=C2N3CCN(CCN4C=C(C)C5=C4C=CC=C5)CC3)=CC(C#N)=C1)NCCCN6CCCC6
InChi
InChI=1S/C36H42N6O/c1-28-27-42(34-11-4-2-9-32(28)34)22-19-40-17-20-41(21-18-40)35-12-5-3-10-33(35)30-23-29(26-37)24-31(25-30)36(43)38-13-8-16-39-14-6-7-15-39/h2-5,9-12,23-25,27H,6-8,13-22H2,1H3,(H,38,43)
InChi Key
PNYRDVBFYVDJJI-UHFFFAOYSA-N

Structure of LLY-507 biochemical

LLY-507 Biochemical – Cat# MBS846255

Other Notes

Small volumes of LLY-507 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LLY-507 purchase

MBS846255 is a biochemical targeting LLY-507.
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