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MYLK3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5400546

Description: Affinity Purified Myosin light chain kinase 3 Antibody Overview: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.Structure: Belongs to the protein kinase… More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MYLK3, Polyclonal Antibody
Full Product Name
MYLK3 Antibody
Product Gene Name
Product Synonym Names
Affinity Purified Myosin light chain kinase 3 Antibody; caMLCK antibody; cardiac MLCK antibody; Cardiac MyBP C associated Ca/CaM kinase antibody; MLC kinase antibody; MLCK antibody; MLCK2 antibody; Mylk3 antibody; Myosin light chain kinase 3 antibody; Putative myosin light chain kinase 3 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified Immunoglobulins
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
100ug of antibody in 180-200ul of antibody stabilization buffer. (lot specific)
Preparation and Storage
Store at -20 degree C for long term storage.
3D Structure
ModBase 3D Structure for Q32MK0
Immunogen
Synthetic peptide taken within amino acid region 10-60 on human Myosin light chain kinase 3 protein.
Conjugation
Unconjugated
Molecular Function
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.
Subcellular Location
Cytoplasm
Applications Tested/Suitable for anti-MYLK3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-MYLK3 antibody
ELISA: 1:50,000
IP: 1:200
WB: 1:2,500-1:5,000

Western Blot (WB) of anti-MYLK3 antibody

Western Blot of MBS5400546 antibody (MYLK-301AP) with mouse heart. 1:500 antibody dilution in DilobufferTM (FGI-1963). Apparent MW of MYLK is 90 kDa
Rabbit Anti-MYLK3 Polyclonal Antibody – Cat# MBS5400546

Other Notes

Small volumes of anti-MYLK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYLK3 purchase

MBS5400546 is an antibody targeting MYLK3. Also known as MYLK3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MYLK3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myosin light chain kinase 3 isoform 2
NCBI Official Synonym Full Names
myosin light chain kinase 3
NCBI Official Symbol
MYLK3
NCBI Official Synonym Symbols
MLCK; MLCK2; caMLCK
UniProt Protein Name
Myosin light chain kinase 3
UniProt Synonym Protein Names
Cardiac-MyBP-C-associated Ca/CaM kinase; Cardiac-MLCK
UniProt Gene Name
MYLK3
UniProt Synonym Gene Names
MLCK; Cardiac-MLCK
NCBI Protein Information
myosin light chain kinase 3

NCBI Summary for MYLK3

Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]

UniProt Comments for MYLK3

Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MYLK3 antibody

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