• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IGF2BP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847757

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
IGF2BP3, Polyclonal Antibody
Full Product Name
Anti-IGF2BP3 Antibody
Product Gene Name
Product Synonym Names
IGF2BP3; CT98; IMP-3; IMP3; KOC; KOC1; VICKZ3; insulin-like growth factor 2 mRNA-binding protein 3
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
Liquid. In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purity/Purification
Affinity purification
Specificity
Affinity purified rabbit polyclonal antibody to IGF2BP3
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
63,705 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (23349828..23509995, complement). Location: 7p11
OMIM
608259
3D Structure
ModBase 3D Structure for O00425
Immunogen
Recombinant fusion protein corresponding to aa300-579 of human IGF2BP3
Applications Tested/Suitable for anti-IGF2BP3 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-IGF2BP3 antibody
IHC 1:50-1:200
IF: 1:50-1:200
WB: 1:500-1:2000
IP: 1:20-1:50

Immunocytochemistry/Immunofluorescence (ICC/IF)) of anti-IGF2BP3 antibody

Rabbit Anti-IGF2BP3 Polyclonal Antibody – Cat# MBS847757

Immunohistochemistry (IHC) of anti-IGF2BP3 antibody

Rabbit Anti-IGF2BP3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS847757

Western Blot (WB) of anti-IGF2BP3 antibody

Rabbit Anti-IGF2BP3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS847757

Western Blot (WB) of anti-IGF2BP3 antibody

Rabbit Anti-IGF2BP3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS847757

Other Notes

Small volumes of anti-IGF2BP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGF2BP3 purchase

MBS847757 is an antibody targeting IGF2BP3. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF2BP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor 2 mRNA-binding protein 3
NCBI Official Synonym Full Names
insulin-like growth factor 2 mRNA binding protein 3
NCBI Official Symbol
IGF2BP3
NCBI Official Synonym Symbols
CT98; IMP3; KOC1; IMP-3; VICKZ3
UniProt Protein Name
Insulin-like growth factor 2 mRNA-binding protein 3
UniProt Synonym Protein Names
IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3
UniProt Gene Name
IGF2BP3
UniProt Synonym Gene Names
IMP3; KOC1; VICKZ3; IGF2 mRNA-binding protein 3; IMP-3; hKOC
UniProt Entry Name
IF2B3_HUMAN
NCBI Protein Information
insulin-like growth factor 2 mRNA-binding protein 3; hKOC; VICKZ family member 3; cancer/testis antigen 98; IGF2 mRNA-binding protein 3; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH

UniProt Comments for IGF2BP3

IGF2BP3: RNA-binding protein that act as a regulator of mRNA translation and stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binds to sequences in the 3'-UTR of CD44 mRNA. Belongs to the RRM IMP/VICKZ family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Spliceosome; Translation

Chromosomal Location of Human Ortholog: 7p11

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: protein binding; mRNA 3'-UTR binding; RNA binding; nucleotide binding; translation regulator activity; mRNA 5'-UTR binding

Biological Process: anatomical structure morphogenesis; mRNA transport; translation; negative regulation of translation; gene expression; regulation of cytokine biosynthetic process
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000