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ENMD-2076

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848236

ENMD-2076 is a selective inhibitor of Aurora A and Flt3 with IC50 values of 14 and 1.86 nM, respectively. Displays 5-fold selectivity for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRalpha. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ENMD-2076, Biochemical
Full Product Name
ENMD-2076
Product Synonym Names
6- (4-methylpiperazin-1-yl)-N- (5-methyl-1H-pyrazol-3-yl)-2-[ (E)-2-phenylethenyl]pyrimidin-4-amine
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
375.47
Solubility
DMSO (~ 18 mg/ml)
Molecular Formula
C??H??N?
CAS Number
934353-76-1
PubChem CID
16041424
SMILES
CC1=CC (=NN1)NC2=NC (=NC (=C2)N3CCN (CC3)C)C=CC4=CC=CC=C4
InChi
InChI=1S/C21H25N7/c1-16-14-20 (26-25-16)23-19-15-21 (28-12-10-27 (2)11-13-28)24-18 (22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3, (H2,22,23,24,25,26)/b9-8+
InChi Key
BLQYVHBZHAISJM-CMDGGOBGSA-N

Product Categories/Family for ENMD-2076 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Aurora Kinase Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of ENMD-2076 biochemical

ENMD-2076 Biochemical – Cat# MBS848236

Product References and Citations for ENMD-2076 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/16041424

Other Notes

Small volumes of ENMD-2076 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENMD-2076 purchase

MBS848236 is a biochemical targeting ENMD-2076.
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