ABT-494 ((3S)

Name: ABT-494 ((3S); MyBioSource
Brand: MyBioSource
SKU: MBS848245
Price: 320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848245

ABT-494 is a potent and selective Janus kinase JAK-1 inhibitor (IC50 = 43 nM). ABT-494 is 74-fold more selective for JAK-1 over JAK-2 and 58-fold more selective for JAK-1 over JAK-3. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ABT-494, Biochemical

Full Product Name

ABT-494

Product Synonym Names

(3S; 4R)-3-ethyl-4- (3H-imidazo[1; 2-a]pyrrolo[2; 3-e]pyrazin-8-yl)-N- (2; 2; 2-trifluoroethyl) pyrrolidine-1-carboxamide; Upadacitinib

Form/Format

Crystalline solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

Store at -20 degree C
Protect from air and light
Shelf life: ~36 months

Molecular Weight

380.37

Solubility

DMSO

Molecular Formula

C??H??F?N?O

CAS Number

1310726-60-3

PubChem CID

58557659

SMILES

CCC1CN (CC1C2=CN=C3N2C4=C (NC=C4)N=C3)C (=O)NCC (F)(F)F

InChi

InChI=1S/C17H19F3N6O/c1-2-10-7-25 (16 (27)24-9-17 (18,19)20)8-11 (10)13-5-22-14-6-23-15-12 (26 (13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3, (H,24,27)/t10-,11+/m1/s1

InChi Key

WYQFJHHDOKWSHR-MNOVXSKESA-N

Product Categories/Family for ABT-494 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; JAK Inhibitors; Enzyme Inhibitors (A-Z); Products; Signaling Pathways; JAk; Stat Signaling; Biochemicals; Biochemicals (A-Z)

Product References and Citations for ABT-494 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/58557659

Other Notes

Small volumes of ABT-494 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABT-494 purchase

MBS848245 is a biochemical targeting ABT-494.