• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PHA-665752

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848350

PHA-665752 is a potent, selective and ATP-competitive inhibitor of MET kinase (IC50 values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk-1, c-abl, FGFR1, EGFR and c-src respectively and > 10000 nM for IGF-IR, PDGFR, AURORA2, PKA, PKBalpha,… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
PHA-665752, Biochemical
Full Product Name
PHA-665752
Product Synonym Names
2R)-1-[[5-[ (Z)-[5-[[ (2; 6-Dichlorophenyl) methyl]sulfonyl]-1; 2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2; 4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2- (1-pyrrolidinylmethyl) pyrrolidine
Form/Format
Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
641.61
Solubility
DMSO (>50 mg/ml)
Molecular Formula
C??H??Cl?N?O?S
CAS Number
477575-56-7
MDL Number
MFCD07772270
PubChem CID
10461815
SMILES
CC1=C (NC (=C1C (=O)N2CCCC2CN3CCCC3)C)C=C4C5=C (C=CC (=C5)S (=O)(=O)CC6=C (C=CC=C6Cl)Cl)NC4=O
InChi
InChI=1S/C32H34Cl2N4O4S/c1-19-29 (35-20 (2)30 (19)32 (40)38-14-6-7-21 (38)17-37-12-3-4-13-37)16-24-23-15-22 (10-11-28 (23)36-31 (24)39)43 (41,42)18-25-26 (33)8-5-9-27 (25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3, (H,36,39)/b24-16-/t21-/m1/s1
InChi Key
OYONTEXKYJZFHA-SSHUPFPWSA-N

Product Categories/Family for PHA-665752 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z); Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Cancer Research; Oncogenic Signaling Pathway; Biochemicals; Biochemicals (A-Z)

Structure of PHA-665752 biochemical

PHA-665752 Biochemical – Cat# MBS848350

Product References and Citations for PHA-665752 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/10461815

Other Notes

Small volumes of PHA-665752 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PHA-665752 purchase

MBS848350 is a biochemical targeting PHA-665752.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000