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Ac-WEHD-AFC

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848493

Ac-WEHD-AFC is a useful fluorogenic substrate for group I caspases (caspase-1, -4, and -5) . Caspase activity can be quantified by fluorescent detection of free AFC that has an excitation maximum at 400 nm and emission maximum at 505 nm. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ac-WEHD-AFC, Biochemical
Full Product Name
Ac-WEHD-AFC
Product Synonym Names
Caspase-1 substrate (fluorogenic); Caspase-5 substrate (fluorogenic)
Form/Format
White to yellow solid
Purity/Purification
>=97% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
838.8
Solubility
DMSO
Molecular Formula
C??H??F?N?O??
CAS Number
210344-99-3
PubChem CID
25108578
SMILES
CC (=O)NC (CC1=CNC2=CC=CC=C21)C (=O)NC (CCC (=O)O)C (=O)NC (CC3=CN=CN3)C (=O)NC (CC (=O)O)C (=O)NC4=CC5=C (C=C4)C (=CC (=O)O5)C (F)(F)F
InChi
InChI=1S/C38H37F3N8O11/c1-18 (50)45-27 (10-19-15-43-25-5-3-2-4-22 (19)25)36 (58)47-26 (8-9-31 (51)52)34 (56)48-28 (11-21-16-42-17-44-21)37 (59)49-29 (14-32 (53)54)35 (57)46-20-6-7-23-24 (38 (39,40)41)13-33 (55)60-30 (23)12-20/h2-7,12-13,15-17,26-29,43H,8-11,14H2,1H3, (H,42,44)(H,45,50)(H,46,57)(H,47,58)(H,48,56)(H,49,59)(H,51,52)(H,53,54)/t26-,27-,28-,29-/m0/s1
InChi Key
NEGOLAGPKZGIKJ-DZUOILHNSA-N

Product References and Citations for Ac-WEHD-AFC biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/25108578

Other Notes

Small volumes of Ac-WEHD-AFC biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ac-WEHD-AFC purchase

MBS848493 is a biochemical targeting Ac-WEHD-AFC.
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