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LY-3200882

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848626

LY-3200882 is a potent and ATP-competitive inhibitor of TGF-beta receptor type 1 (TGF-betaRI). It inhibits TGF-beta-induced SMAD phosphorylation in vitro and in vivo and exhibits antitumor activity in the 4T1-LP triple negative breast cancer orthotopic tumor… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LY-3200882, Biochemical
Full Product Name
LY-3200882
Product Synonym Names
4-[[4-[[1-cyclopropyl-3- (tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-alpha; alpha-dimethyl-2-pyridinemethanol
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
435.53
Solubility
>50 mg/ml (DMSO)
Molecular Formula
C??H??N?O?
CAS Number
1898283-02-7
PubChem CID
121249291
SMILES
CC (C)(C1=NC=CC (=C1)NC2=NC=CC (=C2)OC3=CN (N=C3C4CCOCC4)C5CC5)O
InChi
InChI=1S/C24H29N5O3/c1-24 (2,30)21-13-17 (5-9-25-21)27-22-14-19 (6-10-26-22)32-20-15-29 (18-3-4-18)28-23 (20)16-7-11-31-12-8-16/h5-6,9-10,13-16,18,30H,3-4,7-8,11-12H2,1-2H3, (H,25,26,27)
InChi Key
PNPFMWIDAKQFPY-UHFFFAOYSA-N

Product Categories/Family for LY-3200882 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors  (A-Z); Biochemicals; Biochemicals (A-Z); Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z)

Structure of LY-3200882 biochemical

Ly-3200882 Biochemical – Cat# MBS848626

Product References and Citations for LY-3200882 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/121249291

Other Notes

Small volumes of LY-3200882 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-3200882 purchase

MBS848626 is a biochemical targeting LY-3200882.
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