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Ca-074 ((2S)-1-[ (2S)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849066

CA-074 is an epoxysuccinyl peptide inhibitor of cathepsin B. It selectively inhibits cathepsin B with an IC50 of 2.24 nM over other cysteine proteinases such as cathepsins L and H, and calpains. It inhibits cathepsins H, L and calpain with IC50 values of 172… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CA-074, Biochemical
Full Product Name
CA-074
Product Synonym Names
(2S)-1-[ (2S; 3S)-3-methyl-2-[[ (2S; 3S)-3- (propylcarbamoyl) oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylic acid; Cathepsin B Inhibitor III; N-{[ (2S; 3S)-3- (propylcarbamoyl) oxiran-2-yl]carbonyl}-L-isoleucyl-L-proline
Form/Format
Solid
Purity/Purification
0.98
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
383.44
Solubility
~8 mg/ml in DMSO
Molecular Formula
C??H??N?O?
CAS Number
134448-10-5
PubChem CID
9821383
SMILES
CCCNC (=O)C1C (O1)C (=O)NC (C (C)CC)C (=O)N2CCCC2C (=O)O
InChi
InChI=1S/C18H29N3O6/c1-4-8-19-15 (22)13-14 (27-13)16 (23)20-12 (10 (3)5-2)17 (24)21-9-6-7-11 (21)18 (25)26/h10-14H,4-9H2,1-3H3, (H,19,22)(H,20,23)(H,25,26)/t10-,11-,12-,13-,14-/m0/s1
InChi Key
ZEZGJKSEBRELAS-PEDHHIEDSA-N

Structure of CA-074 biochemical

Ca-074 (2S)-1-[ (2S Biochemical – Cat# MBS849066

Product References and Citations for CA-074 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/9821383

Other Notes

Small volumes of CA-074 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CA-074 purchase

MBS849066 is a biochemical targeting CA-074.
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