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Apolipoprotein A1 (APOA1) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850267

Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma encoded by the APOA1 gene. It is also found in chylomicrons.and synthesized in the liver and small intestine. It participates in the reverse transport of cholesterol… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Apolipoprotein A1 (APOA1), Antibody
Full Product Name
Apolipoprotein A1 Antibody
Product Gene Name
Clone Number
B5-F11
Species Reactivity
Human
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Specificity
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to residues of Apo A1.
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
28kDa
OMIM
105200
3D Structure
ModBase 3D Structure for P02647
Preservative
0.05% Sodium Azide.
Cellular Localization
Secretory Protein
Positive Control
Human Liver
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-APOA1 antibody
Western Blot (WB)
Application Notes for anti-APOA1 antibody
WB: 1:500-1:1000

Testing Data of anti-APOA1 antibody

Anti-APOA1 Antibody – Cat# MBS850267

Product References and Citations for anti-APOA1 antibody

"Gene structure of human apolipoprotein A1."Shoulders C.C., Kornblihtt A.R., Munro B.S., Baralle F.E.Nucleic Acids Res. 11:2827-2837(1983). "The preferential site of non-enzymatic glycation of human apolipoprotein A-I in vivo."Calvo C., Ulloa N., Campos M., Verdugo C., Ayrault-Jarrier M.Clin. Chim. Acta 217:193-198(1993). "Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins." Niederkofler E.E., Tubbs K.A., Kiernan U.A., Nedelkov D., Nelson R.W.J. Lipid Res. 44:630-639(2003).

Other Notes

Small volumes of anti-APOA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOA1 purchase

MBS850267 is an antibody targeting APOA1. Also known as Apolipoprotein A1 Antibody. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for APOA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
apolipoprotein A-I isoform 1 preproprotein
NCBI Official Synonym Full Names
apolipoprotein A1
NCBI Official Symbol
APOA1
NCBI Official Synonym Symbols
apo(a)
UniProt Protein Name
Apolipoprotein A-I
UniProt Synonym Protein Names
Apolipoprotein A1
Protein Family
UniProt Gene Name
APOA1
UniProt Synonym Gene Names
Apo-AI; ApoA-I; ProapoA-I
NCBI Protein Information
apolipoprotein A-I

NCBI Summary for APOA1

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
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UniProt Comments for APOA1

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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