Mouse Anti-PAX8 Antibody – Cat# MBS850772

Figure 1: Western blot analysis using PAX8 mouse mAb against Hela (1), HEK293 (2) and Raji (3) cell lysate.

PAX8 Antibody – Mouse

Name: PAX8 Antibody; Mouse; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS850772
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850772

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in… More details

$380 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PAX8, Antibody

Full Product Name

PAX8 Antibody

Product Gene Name

anti-PAX8 antibody

Product Synonym Names

PAX8

Isotype

IgG1

Clone Number

2D4

Host

Mouse

Species Reactivity

Human

Form/Format

Ascitic fluid containing 0.03% sodium azide.

Preparation and Storage

Store at 4 degree C, for long term storage, store at-20 degree C.

Molecular Weight

60kDa

OMIM

602529

3D Structure

ModBase 3D Structure for Q71U36

Immunogen

Purified recombinant fragment of human PAX8 expressed in E. Coli.

Product Categories/Family for anti-PAX8 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PAX8 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-PAX8 antibody

WB: 1:500-1:2000
ELISA: 1:10000

Other Notes

Small volumes of anti-PAX8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAX8 purchase

MBS850772 is an antibody targeting PAX8. Also known as PAX8 Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PAX8. It may not necessarily be applicable to this product.

NCBI GI #

393715091

NCBI GeneID

7846

NCBI Accession #

NP_001257328.1

UniProt Primary Accession #

Q71U36

UniProt Secondary Accession #

P04687; P05209; A8K0B8; G3V1U9

UniProt Related Accession #

Q71U36

GenBank Nucleotide #

NM_001270399.1

NCBI Official Full Name

tubulin alpha-1A chain isoform 1

NCBI Official Synonym Full Names

tubulin alpha 1a

NCBI Official Symbol

TUBA1A

NCBI Official Synonym Symbols

LIS3; TUBA3; B-ALPHA-1

UniProt Protein Name

Tubulin alpha-1A chain

UniProt Synonym Protein Names

Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain

Protein Family

Paired box protein

UniProt Gene Name

TUBA1A

UniProt Synonym Gene Names

TUBA3

NCBI Protein Information

tubulin alpha-1A chain

NCBI Summary for PAX8

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

UniProt Comments for PAX8

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Research Articles on PAX8

1. Molecular docking studies revealed that 6f interacted and bound ef fi ciently with the colchicine-binding site of tubulin. In addition, 6f treatment induced G2/M cell cycle arrest dose-dependently and subsequently induced cell apoptosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PAX8 antibody

Reference Product	PubMed Publications
PAFAH1B1 antibody	>9 publications with PAX8 and PAFAH1B1
TBCB antibody	>2 publications with PAX8 and TBCB
TUBB2A antibody	>2 publications with PAX8 and TUBB2A
DYNC1H1 antibody	>1 publications with PAX8 and DYNC1H1
UBC antibody	>1 publications with PAX8 and UBC

Pathways associated with anti-PAX8 antibody

Products by Pathway	Pathway Diagram
Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies	Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Centrosome Maturation Pathway antibodies	Centrosome Maturation Pathway Diagram
Chaperonin-mediated Protein Folding Pathway antibodies	Chaperonin-mediated Protein Folding Pathway Diagram
Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies	Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies	Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
G2/M Transition Pathway antibodies	G2/M Transition Pathway Diagram
Gap Junction Pathway antibodies	Gap Junction Pathway Diagram

Diseases associated with anti-PAX8 antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>15 publications with PAX8 and Brain Diseases
Lissencephaly 3 Antibodies	>12 publications with PAX8 and Lissencephaly 3
Disease Models, Animal Antibodies	>3 publications with PAX8 and Disease Models, Animal
Atrophy Antibodies	>2 publications with PAX8 and Atrophy
Lung Diseases Antibodies	>2 publications with PAX8 and Lung Diseases
Fibrosis Antibodies	>2 publications with PAX8 and Fibrosis
Precancerous Conditions Antibodies	>1 publications with PAX8 and Precancerous Conditions
Liver Diseases Antibodies	>1 publications with PAX8 and Liver Diseases
Cognition Disorders Antibodies	>1 publications with PAX8 and Cognition Disorders
Lung Neoplasms Antibodies	>1 publications with PAX8 and Lung Neoplasms

Organs/Tissues associated with anti-PAX8 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>55 publications with PAX8 and Brain
Nerve Antibodies	>10 publications with PAX8 and Nerve
Ganglia Antibodies	>8 publications with PAX8 and Ganglia
Lung Antibodies	>3 publications with PAX8 and Lung
Heart Antibodies	>3 publications with PAX8 and Heart
Liver Antibodies	>3 publications with PAX8 and Liver
Muscle Antibodies	>3 publications with PAX8 and Muscle
Eye Antibodies	>2 publications with PAX8 and Eye
Blood Antibodies	>1 publications with PAX8 and Blood
Intestine Antibodies	>1 publications with PAX8 and Intestine