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PARD3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851054

MBS851054 is an antibody targeting PARD3. Also known as PARD3 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PARD3, Antibody
Full Product Name
PARD3 Antibody
Product Gene Name
Product Synonym Names
Partitioning-defective 3 homolog; PARD-3; PAR-3; Atypical PKC isotype-specific-interacting protein; ASIP; CTCL tumor antigen se2-5; PAR3-alpha; PARD3; PAR3; PAR3A
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PARD3 antibody detects endogenous levels of total PARD3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
149,695 Da
OMIM
182940
3D Structure
ModBase 3D Structure for Q8TEW0
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PARD3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PARD3 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-PARD3 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:20000

Testing Data of anti-PARD3 antibody

Anti-PARD3 Antibody – Cat# MBS851054

Western Blot (WB) of anti-PARD3 antibody

Peptide-+ Western blot analysis of extracts from COLO205 cells, using PARD3 antibody. Immunofluorescence analysis of HepG2 cells, using PARD3 antibody.
Anti-PARD3 Antibody, Western Blot (WB) – Cat# MBS851054

Product References and Citations for anti-PARD3 antibody

Joberty G., Nat. Cell Biol. 2:531-539(2000). Fang C.M., Cell Res. 11:223-229(2001). Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002).

Other Notes

Small volumes of anti-PARD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PARD3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
partitioning defective 3 homolog isoform 2
NCBI Official Synonym Full Names
par-3 family cell polarity regulator
NCBI Official Symbol
PARD3
NCBI Official Synonym Symbols
Baz; ASIP; PAR3; PARD-3; PARD3A; SE2-5T2; PPP1R118; SE2-5L16; SE2-5LT1; PAR3alpha
UniProt Protein Name
Partitioning defective 3 homolog
UniProt Synonym Protein Names
Atypical PKC isotype-specific-interacting protein; ASIP; CTCL tumor antigen se2-5; PAR3-alpha
Protein Family
UniProt Gene Name
PARD3
UniProt Synonym Gene Names
PAR-3; PARD-3; ASIP
NCBI Protein Information
partitioning defective 3 homolog

NCBI Summary for PARD3

This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for PARD3

Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (). Involved in Schwann cell peripheral myelination (). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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