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CEP152 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852949

MBS852949 is an antibody targeting CEP152. Also known as CEP152 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CEP152, Antibody
Full Product Name
CEP152 Antibody
Product Gene Name
Product Synonym Names
CE152; centrosomal protein 152 kDa; centrosomal protein 152kDa; centrosomal protein of 152 kDa
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CEP152 antibody detects endogenous levels of total CEP152 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
189,071 Da
OMIM
613529
3D Structure
ModBase 3D Structure for O94986
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CEP152.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CEP152 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CEP152 antibody
IHC: 1:50-1:100
ELISA: 1:40000

Immunohistochemistry (IHC) of anti-CEP152 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using CEP152 antibody.
Anti-CEP152 Antibody – Cat# MBS852949

Product References and Citations for anti-CEP152 antibody

Nagase T., DNA Res. 5:355-364(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004). Andersen J.S., Nature 426:570-574(2003).

Other Notes

Small volumes of anti-CEP152 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CEP152. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centrosomal protein of 152 kDa isoform 1
NCBI Official Synonym Full Names
centrosomal protein 152
NCBI Official Symbol
CEP152
NCBI Official Synonym Symbols
MCPH4; MCPH9; SCKL5
UniProt Protein Name
Centrosomal protein of 152 kDa
Protein Family
UniProt Gene Name
CEP152
UniProt Synonym Gene Names
KIAA0912; Cep152
NCBI Protein Information
centrosomal protein of 152 kDa

NCBI Summary for CEP152

This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

UniProt Comments for CEP152

Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles (). Overexpression of CEP152 can drive amplification of centrioles (PubMed:20852615).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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