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Glucokinase Regulator (GCKR) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853319

MBS853319 is an antibody targeting GCKR. Also known as Glucokinase Regulator Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glucokinase Regulator (GCKR), Antibody
Full Product Name
Glucokinase Regulator Antibody
Product Gene Name
Product Synonym Names
Glucokinase regulatory protein; Glucokinase regulator
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Glucokinase Regulator antibody detects endogenous levels of total Glucokinase Regulator protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
16,477 Da
OMIM
600842
3D Structure
ModBase 3D Structure for Q14397
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human Glucokinase Regulator.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GCKR antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GCKR antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot (WB) of anti-GCKR antibody

Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibody.
Anti-GCKR Antibody – Cat# MBS853319

Product References and Citations for anti-GCKR antibody

Warner J.P., Mamm. Genome 6:532-536(1995). Hayward B.E., Genomics 49:137-142(1998). Rieder M.J., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-GCKR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GCKR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glucokinase regulatory protein
NCBI Official Synonym Full Names
glucokinase regulator
NCBI Official Symbol
GCKR
NCBI Official Synonym Symbols
GKRP; FGQTL5
UniProt Protein Name
Glucokinase regulatory protein
UniProt Gene Name
GCKR
UniProt Synonym Gene Names
GKRP; Glucokinase regulator
NCBI Protein Information
glucokinase regulatory protein

NCBI Summary for GCKR

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]
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UniProt Comments for GCKR

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GCKR antibody

 Reference Product  PubMed Publications
 GCK antibody  >35 publications with GCKR and GCK
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