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TALL-2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853329

MBS853329 is an antibody targeting TALL-2. Also known as TALL-2 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TALL-2, Antibody
Full Product Name
TALL-2 Antibody
Product Gene Name
anti-TALL-2 antibody
Product Synonym Names
Tumor necrosis factor ligand superfamily member 13 [Precursor]; A proliferation-inducing ligand; APRIL; TNF-and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256 antigen; TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TALL-2 antibody detects endogenous levels of total TALL-2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
36,589 Da
OMIM
604472
3D Structure
ModBase 3D Structure for O75888
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TALL-2.

Product Categories/Family for anti-TALL-2 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TALL-2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-TALL-2 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:10000

Testing Data of anti-TALL-2 antibody

Peptide-+
Anti-TALL-2 Antibody – Cat# MBS853329

Immunohistochemistry (IHC) of anti-TALL-2 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TALL-2 antibody. Western blot analysis of extracts from HeLa cells and COLO205 cells, using TALL-2 antibody.
Anti-TALL-2 Antibody, Immunohistochemistry (IHC) – Cat# MBS853329

Immunofluorescence (IF) of anti-TALL-2 antibody

Peptide-+ Immunofluorescence analysis of HeLa cells, using TALL-2 antibody.
Anti-TALL-2 Antibody, Immunofluorescence (IF) – Cat# MBS853329

Product References and Citations for anti-TALL-2 antibody

Hahne M., J. Exp. Med. 188:1185-1190(1998). Shu H.-B., J. Leukoc. Biol. 65:680-683(1999). Kelly K.A., Cancer Res. 60:1021-1027(2000).

Other Notes

Small volumes of anti-TALL-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TALL-2. It may not necessarily be applicable to this product.

NCBI GI #
310750387
NCBI GeneID
8741
NCBI Accession #
NP_001185552.1
UniProt Primary Accession #
O75888
UniProt Secondary Accession #
Q541E1; Q5U0G8; Q96HV6; Q9P1M8; Q9P1M9; A8MYD5; B4DVT2
UniProt Related Accession #
O75888
GenBank Nucleotide #
NM_001198623.1
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 13 isoform zeta
NCBI Official Synonym Full Names
TNF superfamily member 13
NCBI Official Symbol
TNFSF13
NCBI Official Synonym Symbols
APRIL; CD256; TALL2; ZTNF2; TALL-2; TNLG7B; TRDL-1; UNQ383/PRO715
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 13
UniProt Synonym Protein Names
A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD_antigen: CD256
UniProt Gene Name
TNFSF13
UniProt Synonym Gene Names
APRIL; TALL2; ZTNF2; APRIL; TALL-2; TRDL-1
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13

NCBI Summary for TALL-2

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
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UniProt Comments for TALL-2

Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.

Research Articles on TALL-2

1. The genetic variations and gene expression level of TNFSF13 are associated with the susceptibility and severity of IgA nephropathy in a Han Chinese population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TALL-2 antibody

 Reference Product  PubMed Publications
 TNFSF13B antibody  >89 publications with TALL-2 and TNFSF13B
 TNFRSF17 antibody  >55 publications with TALL-2 and TNFRSF17
 TNFRSF13B antibody  >43 publications with TALL-2 and TNFRSF13B
 FURIN antibody  >5 publications with TALL-2 and FURIN
 TNFRSF11B antibody  >2 publications with TALL-2 and TNFRSF11B
 FAS antibody  >2 publications with TALL-2 and FAS

Pathways associated with anti-TALL-2 antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
 Stabilization Of MRNA By HuR Pathway antibodies  Stabilization Of MRNA By HuR Pathway Diagram

Diseases associated with anti-TALL-2 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >191 publications with TALL-2 and Necrosis
 Neoplasms Antibodies  >64 publications with TALL-2 and Neoplasms
 Inflammation Antibodies  >20 publications with TALL-2 and Inflammation
 Disease Models, Animal Antibodies  >12 publications with TALL-2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >11 publications with TALL-2 and Cardiovascular Diseases
 Multiple Myeloma Antibodies  >10 publications with TALL-2 and Multiple Myeloma
 Nervous System Diseases Antibodies  >7 publications with TALL-2 and Nervous System Diseases
 Colorectal Neoplasms Antibodies  >6 publications with TALL-2 and Colorectal Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with TALL-2 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >4 publications with TALL-2 and Kidney Diseases

Organs/Tissues associated with anti-TALL-2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >148 publications with TALL-2 and Blood
 Bone Antibodies  >17 publications with TALL-2 and Bone
 Spleen Antibodies  >15 publications with TALL-2 and Spleen
 Lung Antibodies  >9 publications with TALL-2 and Lung
 Kidney Antibodies  >8 publications with TALL-2 and Kidney
 Lymph Node Antibodies  >8 publications with TALL-2 and Lymph Node
 Skin Antibodies  >6 publications with TALL-2 and Skin
 Vascular Antibodies  >5 publications with TALL-2 and Vascular
 Liver Antibodies  >4 publications with TALL-2 and Liver
 Thymus Antibodies  >3 publications with TALL-2 and Thymus
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