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MYO9B Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853394

MBS853394 is an antibody targeting MYO9B. Also known as MYO9B Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MYO9B, Antibody
Full Product Name
MYO9B Antibody
Product Gene Name
Product Synonym Names
Myosin-Ixb; Unconventional myosin-9b
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MYO9B antibody detects endogenous levels of total MYO9B protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
229,143 Da
OMIM
602129
3D Structure
ModBase 3D Structure for Q13459
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human MYO9B.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MYO9B antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MYO9B antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-MYO9B antibody

Western blot analysis of extracts from HeLa cells and Jurkat cells, using MYO9B antibody. For Research Use Only
Anti-MYO9B Antibody – Cat# MBS853394

Product References and Citations for anti-MYO9B antibody

Wirth J.A., J. Cell Sci. 109:653-661(1996). Grewal P.K., Gene 240:389-398(1999). Post P.L., J. Cell Sci. 111:941-950(1998).

Other Notes

Small volumes of anti-MYO9B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MYO9B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
unconventional myosin-IXb isoform 1
NCBI Official Synonym Full Names
myosin IXB
NCBI Official Symbol
MYO9B
NCBI Official Synonym Symbols
MYR5; CELIAC4
UniProt Protein Name
Unconventional myosin-IXb
UniProt Synonym Protein Names
Unconventional myosin-9b
Protein Family
UniProt Gene Name
MYO9B
UniProt Synonym Gene Names
MYR5
NCBI Protein Information
unconventional myosin-IXb

NCBI Summary for MYO9B

This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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UniProt Comments for MYO9B

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1; interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MYO9B antibody

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