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NUP93 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853422

MBS853422 is an antibody targeting NUP93. Also known as NUP93 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NUP93, Antibody
Full Product Name
NUP93 Antibody
Product Gene Name
anti-NUP93 antibody
Product Synonym Names
Nuclear pore complex protein Nup93; Nucleoporin Nup93; 93 kDa nucleoporin
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NUP93 antibody detects endogenous levels of total NUP93 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
79,882 Da
OMIM
614351
3D Structure
ModBase 3D Structure for Q8N1F7
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human NUP93.

Product Categories/Family for anti-NUP93 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NUP93 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-NUP93 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-NUP93 antibody

Western blot analysis of extracts from rat liver cells, using NUP93 antibody. For Research Use Only
Anti-NUP93 Antibody – Cat# MBS853422

Product References and Citations for anti-NUP93 antibody

Nagase T., DNA Res. 2:37-43(1995). Grandi P., Mol. Biol. Cell 8:2017-2038(1997). Yu L.-R., J. Proteome Res. 6:4150-4162(2007).

Other Notes

Small volumes of anti-NUP93 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NUP93. It may not necessarily be applicable to this product.

NCBI GI #
338753429
NCBI GeneID
9688
NCBI Accession #
NP_001229724.1
UniProt Primary Accession #
Q8N1F7
UniProt Secondary Accession #
Q14705; B3KPQ8
UniProt Related Accession #
Q8N1F7
GenBank Nucleotide #
NM_001242795.1
NCBI Official Full Name
nuclear pore complex protein Nup93 isoform 2
NCBI Official Synonym Full Names
nucleoporin 93
NCBI Official Symbol
NUP93
NCBI Official Synonym Symbols
NIC96
UniProt Protein Name
Nuclear pore complex protein Nup93
UniProt Synonym Protein Names
93 kDa nucleoporin; Nucleoporin Nup93
Protein Family
Nuclear pore complex protein
UniProt Gene Name
NUP93
UniProt Synonym Gene Names
KIAA0095
NCBI Protein Information
nuclear pore complex protein Nup93

NCBI Summary for NUP93

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
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UniProt Comments for NUP93

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540). May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725).

Research Articles on NUP93

1. we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NUP93 antibody

 Reference Product  PubMed Publications
 NUP205 antibody  >8 publications with NUP93 and NUP205
 NDC1 antibody  >2 publications with NUP93 and NDC1

Pathways associated with anti-NUP93 antibody

 Products by Pathway  Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies  Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Host Interactions Of HIV Factors Pathway antibodies  Host Interactions Of HIV Factors Pathway Diagram

Diseases associated with anti-NUP93 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1 publications with NUP93 and Cardiovascular Diseases
 Death Antibodies  >1 publications with NUP93 and Death
 Neoplasms Antibodies  >1 publications with NUP93 and Neoplasms
 Congenital Abnormalities Antibodies  >1 publications with NUP93 and Congenital Abnormalities
 Heart Failure Antibodies  >1 publications with NUP93 and Heart Failure
 Nervous System Diseases Antibodies  >1 publications with NUP93 and Nervous System Diseases
 Heart Defects, Congenital Antibodies  >1 publications with NUP93 and Heart Defects, Congenital

Organs/Tissues associated with anti-NUP93 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2 publications with NUP93 and Heart
 Muscle Antibodies  >1 publications with NUP93 and Muscle
 Liver Antibodies  >1 publications with NUP93 and Liver
 Kidney Antibodies  >1 publications with NUP93 and Kidney
 Thymus Antibodies  >1 publications with NUP93 and Thymus
 Testis Antibodies  >1 publications with NUP93 and Testis
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