• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GLR Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853441

MBS853441 is an antibody targeting GLR. Also known as GLR Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GLR, Antibody
Full Product Name
GLR Antibody
Product Gene Name
anti-GLR antibody
Product Synonym Names
Glucagon receptor [Precursor]; GL-R; GCGR
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GLR antibody detects endogenous levels of total GLR protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
54,009 Da
OMIM
138033
3D Structure
ModBase 3D Structure for P47871
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GLR.

Product Categories/Family for anti-GLR antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GLR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GLR antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-GLR antibody

Anti-GLR Antibody – Cat# MBS853441

Western Blot (WB) of anti-GLR antibody

Peptide-+ Western blot analysis of extracts from COLO205 cells, using GLR antibody. Immunofluorescence analysis of HeLa cells, using GLR antibody.
Anti-GLR Antibody, Western Blot (WB) – Cat# MBS853441

Product References and Citations for anti-GLR antibody

Macneil D.J., Biochem. Biophys. Res. Commun. 198:328-334(1994). Lok S., Gene 140:203-209(1994). Menzel S., Genomics 20:327-328(1994).

Other Notes

Small volumes of anti-GLR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLR. It may not necessarily be applicable to this product.

NCBI GI #
4503947
NCBI GeneID
2642
NCBI Accession #
NP_000151.1
UniProt Primary Accession #
P47871
UniProt Secondary Accession #
Q2M3M5
UniProt Related Accession #
P47871
GenBank Nucleotide #
NM_000160.4
NCBI Official Full Name
glucagon receptor
NCBI Official Synonym Full Names
glucagon receptor
NCBI Official Symbol
GCGR
NCBI Official Synonym Symbols
GGR; GL-R
UniProt Protein Name
Glucagon receptor
UniProt Gene Name
GCGR
UniProt Synonym Gene Names
GL-R
NCBI Protein Information
glucagon receptor

NCBI Summary for GLR

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

UniProt Comments for GLR

G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Show more

Research Articles on GLR

1. 3.0 A-resolution crystal structure of the full-length human glucagon receptor (GCGR) in complex with a glucagon analogue and partial agonist, NNC1702

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLR antibody

 Reference Product  PubMed Publications
 GCG antibody  >4 publications with GLR and GCG

Pathways associated with anti-GLR antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glucagon Signaling In Metabolic Regulation Pathway antibodies  Glucagon Signaling In Metabolic Regulation Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram

Diseases associated with anti-GLR antibody

 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >13 publications with GLR and Hyperplasia
 Diabetes Mellitus, Type 2 Antibodies  >8 publications with GLR and Diabetes Mellitus, Type 2
 Weight Loss Antibodies  >7 publications with GLR and Weight Loss
 Fatty Liver Antibodies  >4 publications with GLR and Fatty Liver
 Death Antibodies  >4 publications with GLR and Death
 Hypertension Antibodies  >4 publications with GLR and Hypertension
 Cardiovascular Diseases Antibodies  >4 publications with GLR and Cardiovascular Diseases
 Hypertrophy Antibodies  >2 publications with GLR and Hypertrophy
 Liver Diseases Antibodies  >2 publications with GLR and Liver Diseases
 Inflammation Antibodies  >1 publications with GLR and Inflammation

Organs/Tissues associated with anti-GLR antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >22 publications with GLR and Liver
 Pancreas Antibodies  >18 publications with GLR and Pancreas
 Kidney Antibodies  >3 publications with GLR and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000