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DOK7 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854681

MBS854681 is an antibody targeting DOK7. Also known as DOK7 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DOK7, Antibody
Full Product Name
DOK7 Antibody
Product Gene Name
Product Synonym Names
Dok-7; downstream of tyrosine kinase 7
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DOK7 antibody detects endogenous levels of total DOK7 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
63,938 Da
OMIM
254300
3D Structure
ModBase 3D Structure for Q18PE1
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human DOK7.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DOK7 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-DOK7 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-DOK7 antibody

Peptide-+
Anti-DOK7 Antibody – Cat# MBS854681

Immunohistochemistry (IHC) of anti-DOK7 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using DOK7 antibody. Western blot analysis of extracts from mouse brain cells, using DOK7 antibody.
Anti-DOK7 Antibody, Immunohistochemistry (IHC) – Cat# MBS854681

Immunofluorescence (IF) of anti-DOK7 antibody

Peptide-+ Immunofluorescence analysis of HepG2 cells, using DOK7 antibody.
Anti-DOK7 Antibody, Immunofluorescence (IF) – Cat# MBS854681

Product References and Citations for anti-DOK7 antibody

Okada K., Science 312:1802-1805(2006). Ota T., Nat. Genet. 36:40-45(2004). Beeson D., Science 313:1975-1978(2006).

Other Notes

Small volumes of anti-DOK7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DOK7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein Dok-7 isoform 2
NCBI Official Synonym Full Names
docking protein 7
NCBI Official Symbol
DOK7
NCBI Official Synonym Symbols
CMS10; CMS1B; C4orf25
UniProt Protein Name
Protein Dok-7
UniProt Synonym Protein Names
Downstream of tyrosine kinase 7
Protein Family
UniProt Gene Name
DOK7
UniProt Synonym Gene Names
C4orf25
NCBI Protein Information
protein Dok-7

NCBI Summary for DOK7

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
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UniProt Comments for DOK7

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DOK7 antibody

 Reference Product  PubMed Publications
 MUSK antibody  >25 publications with DOK7 and MUSK

Organs/Tissues associated with anti-DOK7 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with DOK7 and Eye
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