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PLD2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855468

MBS855468 is an antibody targeting PLD2. Also known as PLD2 (Phospho-Tyr169) Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLD2, Antibody
Full Product Name
PLD2 (Phospho-Tyr169) Antibody
Product Gene Name
Product Synonym Names
choline phosphatase 2; EC 3.1.4.4; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D2; PLD 2; PLD1C
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
PLD2 (Phospho-Tyr169) antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
104,657 Da
OMIM
602384
3D Structure
ModBase 3D Structure for O14939
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human PLD2 around the phosphorylation site of tyrosine 169 (E-N-YP-L-N).
All Sites
Human: Tyr169
Mouse: Tyr169
Rat: Tyr169
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PLD2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-PLD2 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data of anti-PLD2 antibody

P-peptide-+
Anti-PLD2 Antibody – Cat# MBS855468

Immunohistochemistry (IHC) of anti-PLD2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using PLD2 (Phospho-Tyr169) antibody. Western blot analysis of extracts from Jurkat cells, treated with TNF (20ng/ml, 30mins), using PLD2 (Phospho-Tyr169) antibody.
Anti-PLD2 Antibody, Immunohistochemistry (IHC) – Cat# MBS855468

Product References and Citations for anti-PLD2 antibody

Steed P.M., FASEB J. 12:1309-1317(1998). Lopez I., J. Biol. Chem. 273:12846-12852(1998). Divecha N., EMBO J. 19:5440-5449(2000).

Other Notes

Small volumes of anti-PLD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phospholipase D2 isoform PLD2B
NCBI Official Synonym Full Names
phospholipase D2
NCBI Official Symbol
PLD2
NCBI Official Synonym Symbols
PLD1C
UniProt Protein Name
Phospholipase D2
UniProt Synonym Protein Names
Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2
Protein Family
UniProt Gene Name
PLD2
UniProt Synonym Gene Names
PLD 2; hPLD2
NCBI Protein Information
phospholipase D2

NCBI Summary for PLD2

The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
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UniProt Comments for PLD2

May have a role in signal-induced cytoskeletal regulation and/or endocytosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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