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E2F8 cDNA Clone – E2F Transcription Factor 8 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268012

MBS1268012 is a cDNA clone targeting E2F8. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
E2F8, cDNA Clone
Full Product Name
E2F8 cDNA Clone
Product Gene Name
E2F8 cdna clone
Sequence
atggctcagc ttgcagctat ttgtaaaatg cagttagaag agcaatcaag tgaatccaga cagaaagtga aagtacagct ggcaagatct ggaccctgca aaccagtagc ccctctggac cccccagtga atgctgagat ggagctgaca gcaccgtccc tcatccagcc cctgggaatg gttcccctga tccccagccc cttgtcatca gcagtgcccc tgatcctacc tcaggcccct tcaggcccat cctatgccat ctacctgcag cccactcaag cccaccaaag tgtgacgcca ccccaaggcc tgagcccaac ggtgtgcacc acccactctt ctaaagctac tggctcaaaa gactccacag atgccaccac tgagaaggca gccaatgata cctcaaaggc cagtgcctct accaggcctg gaagcttgct gccagcacca gagaggcaag gggcaaagag ccgaaccagg gagccagctg gagaaagagg ctcaaagagg gcaagcatgc tcgaggacag tggttccaaa aagaaattta aagaggacct aaaaggactt gaaaatgtct ccgcaacctt gttcccatca ggatacctaa tccctctcac gcagtgctca tccctggggg cagagtccat tttgtctggt aaagaaaact caagtgctct ttccccaaac cacaggattt acagctcccc aattgcaggt gttattccag tgacatcatc tgaactcact gctgttaatt ttccctcttt tcatgtaaca ccgttgaagc taatggtctc accaacttcc gtggcagccg tacctgtcgg gaacagcccg gctctcgctt caagccaccc tgttcccatc cagaacccaa gctcagccat tgtaaacttc accctgcagc acctgggact catctcaccc aatgtgcagt tgtctgccag ccctgggtct ggaatcgttc ctgtgtctcc aagaatagag tctgttaatg tcgcaccaga aaatgcaggc actcagcaag gaagggccac caactatgac tcaccagtcc caggccagag ccagccaaat ggacaatcag ttgctgtgac aggggcacaa cagcctgttc ctgtgacacc caaagggtca caattagtgg ccgaaagttt cttccgtacc ccaggtggac ccaccaagcc aaccagctca tcctgcatgg attttgaggg tgctaataaa acctccttag gaactctctt tgtcccacag cgaaaactgg aagtctcaac agaggatgtc cattaa
Molecular Weight
94,166 Da
OMIM
612047
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of E2F8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for E2F8. It may not necessarily be applicable to this product.

NCBI GI #
20380073
NCBI GeneID
79733
NCBI Accession #
BC028244
UniProt Secondary Accession #
Q2VPJ3; Q3C1U6; Q5BKY4; Q8N340; Q9H5M0; A8K9H3
UniProt Related Accession #
A0AVK6
NCBI Official Full Name
Homo sapiens E2F transcription factor 8, mRNA
NCBI Official Synonym Full Names
E2F transcription factor 8
NCBI Official Symbol
E2F8
NCBI Official Synonym Symbols
E2F-8
UniProt Protein Name
Transcription factor E2F8
Protein Family
Transcription factor
UniProt Gene Name
E2F8
UniProt Synonym Gene Names
E2F-8
UniProt Entry Name
E2F8_HUMAN
NCBI Protein Information
transcription factor E2F8

NCBI Summary for E2F8

This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]
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UniProt Comments for E2F8

E2F8: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 11p15.1

Molecular Function: protein binding; transcription corepressor activity; transcription factor activity

Biological Process: cell cycle comprising mitosis without cytokinesis; negative regulation of cytokinesis; negative regulation of transcription from RNA polymerase II promoter; placenta development; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis
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Research Articles on E2F8

1. transcription factor E2F8 is involved in the polyploidization during mouse and human decidualization

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with E2F8 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with E2F8 and Neoplasms
 Carcinoma Antibodies  >2 publications with E2F8 and Carcinoma
 Adenocarcinoma Antibodies  >2 publications with E2F8 and Adenocarcinoma
 Liver Diseases Antibodies  >2 publications with E2F8 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with E2F8 and Carcinoma, Hepatocellular
 Anemia Antibodies  >1 publications with E2F8 and Anemia
 Carcinoma, Squamous Cell Antibodies  >1 publications with E2F8 and Carcinoma, Squamous Cell
 Ovarian Diseases Antibodies  >1 publications with E2F8 and Ovarian Diseases
 Disease Models, Animal Antibodies  >1 publications with E2F8 and Disease Models, Animal
 Liver Neoplasms Antibodies  >1 publications with E2F8 and Liver Neoplasms

Organs/Tissues associated with E2F8 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >5 publications with E2F8 and Embryonic Tissue
 Lung Antibodies  >1 publications with E2F8 and Lung
 Uterus Antibodies  >1 publications with E2F8 and Uterus
 Placenta Antibodies  >1 publications with E2F8 and Placenta
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