Cathepsin L1 (CTSL1) ELISA Kit for Rat

Name: Rat CTSL1 ELISA Kit; Cathepsin L1; MyBioSource
Brand: MyBioSource
SKU: MBS922239
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS922239

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for cTn-I has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any cTn-I present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

cathepsin L1 (CTSL1), ELISA Kit

Full Product Name

Rat Cathepsin L1, CTSL1 ELISA Kit

Product Gene Name

CTSL1 elisa kit

Product Synonym Names

Rat Cathepsin L1 (CTSL1) ELISA kit; CATL; CTSL; FLJ31037; MEP; cathepsin L; major excreted protein; cathepsin L1

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, Plasma, Tissue Homogenates

Detection Range

15.6 pg/ml-1000 pg/ml

Sensitivity

3.9 pg/ml.

Specificity

This assay has high sensitivity and excellent specificity for detection of pig cTn-I. No significant cross-reactivity or interference between pig cTn-I and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess

Molecular Weight

37,660 Da

3D Structure

ModBase 3D Structure for P07154

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CTSL1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTSL1 purchase

MBS922239 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cathepsin L1 (CTSL1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CTSL1. The ELISA analytical biochemical technique of the MBS922239 kit is based on CTSL1 antibody-CTSL1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTSL1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTSL1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CTSL1. It may not necessarily be applicable to this product.

NCBI GI #

6978723

NCBI GeneID

25697

NCBI Accession #

NP_037288.1

UniProt Primary Accession #

P07154

UniProt Secondary Accession #

Q9QV07

UniProt Related Accession #

P07154

GenBank Nucleotide #

NM_013156.2

NCBI Official Full Name

cathepsin L1 preproprotein

NCBI Official Synonym Full Names

cathepsin L

NCBI Official Symbol

Ctsl

NCBI Official Synonym Symbols

CatL; CATHL; Ctsl1

UniProt Protein Name

Cathepsin L1

UniProt Synonym Protein Names

Cathepsin L; Cyclic protein 2; CP-2; Major excreted protein; MEP

Protein Family

Cathepsin

UniProt Gene Name

Ctsl

UniProt Synonym Gene Names

Ctsl1; CP-2; MEP

UniProt Entry Name

CATL1_RAT

NCBI Protein Information

cathepsin L1; MEP; CP-2; cyclic protein 2; major excreted protein

NCBI Summary for CTSL1

mouse homolog is deleted in the CD4 T-cell-deficient mouse mutant nacht (nkt); may play a role in CD4+ T-cell selection in the thymus [RGD, Feb 2006]

UniProt Comments for CTSL1

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.

Protein type: Protease; Secreted; EC 3.4.22.15; Secreted, signal peptide

Cellular Component: extracellular space; neuron projection; microvillus; apical part of cell; lysosome; cytoplasm; nucleolus; perikaryon; vacuole; cytoplasmic vesicle; nucleus; secretory granule; external side of plasma membrane

Molecular Function: collagen binding; proteoglycan binding; histone binding; fibronectin binding; cysteine-type endopeptidase activity; protein complex binding; cysteine-type carboxypeptidase activity; aminopeptidase activity; kininogen binding; peptide binding; cysteine-type peptidase activity

Biological Process: adaptive immune response; hair follicle morphogenesis; male gonad development; response to glucocorticoid stimulus; Sertoli cell differentiation; multicellular organismal aging; decidualization; cellular response to starvation; proteolysis; response to organic cyclic substance; collagen catabolic process; protein autoprocessing; proteolysis involved in cellular protein catabolic process; response to glucose stimulus; autophagic cell death; cell communication; nerve development; spermatogenesis; protein processing

Research Articles on CTSL1

1. Changes in olfaction were less consistent and widespread in the hippocampus, but were again sex specific for three genes: cathepsin-L (CtsL), matrix metalloproteinase-14 (MMP-14) and MMP-16.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CTSL1 elisa kit

Products by Pathway	Pathway Diagram
Antigen Processing And Presentation Pathway antibodies	Antigen Processing And Presentation Pathway Diagram
Antigen Processing And Presentation Pathway antibodies	Antigen Processing And Presentation Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Rheumatoid Arthritis Pathway antibodies	Rheumatoid Arthritis Pathway Diagram
Rheumatoid Arthritis Pathway antibodies	Rheumatoid Arthritis Pathway Diagram

Diseases associated with CTSL1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>48 publications with CTSL1 and Nervous System Diseases
Gastrointestinal Diseases Antibodies	>40 publications with CTSL1 and Gastrointestinal Diseases
Brain Diseases Antibodies	>31 publications with CTSL1 and Brain Diseases
Breast Neoplasms Antibodies	>28 publications with CTSL1 and Breast Neoplasms
Liver Diseases Antibodies	>16 publications with CTSL1 and Liver Diseases
Necrosis Antibodies	>15 publications with CTSL1 and Necrosis
Kidney Diseases Antibodies	>14 publications with CTSL1 and Kidney Diseases
Neuromuscular Diseases Antibodies	>12 publications with CTSL1 and Neuromuscular Diseases
Heart Diseases Antibodies	>9 publications with CTSL1 and Heart Diseases
Muscular Diseases Antibodies	>9 publications with CTSL1 and Muscular Diseases

Organs/Tissues associated with CTSL1 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>65 publications with CTSL1 and Liver
Lung Antibodies	>43 publications with CTSL1 and Lung
Kidney Antibodies	>42 publications with CTSL1 and Kidney
Brain Antibodies	>38 publications with CTSL1 and Brain
Muscle Antibodies	>36 publications with CTSL1 and Muscle
Connective Tissue Antibodies	>20 publications with CTSL1 and Connective Tissue
Spleen Antibodies	>18 publications with CTSL1 and Spleen
Ovary Antibodies	>14 publications with CTSL1 and Ovary
Heart Antibodies	>12 publications with CTSL1 and Heart
Placenta Antibodies	>11 publications with CTSL1 and Placenta