Ferritin, Heavy Polypeptide 1 (FTH1) ELISA Kit for Mouse

Name: Mouse FTH1 ELISA Kit; Ferritin, Heavy Polypeptide 1; MyBioSource
Brand: MyBioSource
SKU: MBS931412
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS931412

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FTH1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FTH1 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

ferritin, heavy polypeptide 1 (FTH1), ELISA Kit

Full Product Name

Mouse Ferritin heavy chain, FTH1 ELISA Kit

Product Gene Name

FTH1 elisa kit

Product Synonym Names

Mouse Ferritin heavy chain (FTH1) ELISA kit; FHC; FTH; FTHL6; MGC104426; PIG15; PLIF; apoferritin; placenta immunoregulatory factor; proliferation-inducing protein 15; ferritin; heavy polypeptide 1

Species Reactivity

Mouse

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

0.312 ng/ml-20 ng/ml

Sensitivity

< 0.078 ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of mouse FTH1. No significant cross-reactivity or interference between mouse FTH1 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

21,067 Da

3D Structure

ModBase 3D Structure for P09528

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FTH1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FTH1 purchase

MBS931412 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ferritin, heavy polypeptide 1 (FTH1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FTH1. The ELISA analytical biochemical technique of the MBS931412 kit is based on FTH1 antibody-FTH1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FTH1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FTH1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FTH1. It may not necessarily be applicable to this product.

NCBI GI #

6753912

NCBI GeneID

14319

NCBI Accession #

NP_034369.1

UniProt Primary Accession #

P09528

UniProt Secondary Accession #

Q3UI44

UniProt Related Accession #

P09528

GenBank Nucleotide #

NM_010239.2

NCBI Official Full Name

ferritin heavy chain

NCBI Official Synonym Full Names

ferritin heavy chain 1

NCBI Official Symbol

Fth1

NCBI Official Synonym Symbols

FHC; Fth; HFt; MFH

UniProt Protein Name

Ferritin heavy chain

Protein Family

Iron transporter

UniProt Gene Name

Fth1

UniProt Synonym Gene Names

Fth; Ferritin H subunit

UniProt Entry Name

FRIH_MOUSE

NCBI Protein Information

ferritin heavy chain; H-ferritin; ferritin H subunit

UniProt Comments for FTH1

Ferritin-H: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. Belongs to the ferritin family.

Protein type: Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.16.3.1

Cellular Component: mitochondrion; nucleus

Molecular Function: ferroxidase activity; ferric iron binding; metal ion binding; oxidoreductase activity

Biological Process: cellular iron ion homeostasis; negative regulation of fibroblast proliferation; iron ion transport; intracellular sequestering of iron ion

Research Articles on FTH1

1. 3-Hydroxybutyrate dehydrogenase-2 and ferritin-H synergistically regulate intracellular iron.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FTH1 elisa kit

Reference Product	PubMed Publications
Tfrc elisa kit	>2 publications with FTH1 and Tfrc
Fech elisa kit	>2 publications with FTH1 and Fech

Pathways associated with FTH1 elisa kit

Products by Pathway	Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Golgi Associated Vesicle Biogenesis Pathway antibodies	Golgi Associated Vesicle Biogenesis Pathway Diagram
Iron Homeostasis Pathway antibodies	Iron Homeostasis Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Scavenging By Class A Receptors Pathway antibodies	Scavenging By Class A Receptors Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with FTH1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with FTH1 and Inflammation
Liver Diseases Antibodies	>4 publications with FTH1 and Liver Diseases
Iron Overload Antibodies	>4 publications with FTH1 and Iron Overload
Disease Models, Animal Antibodies	>3 publications with FTH1 and Disease Models, Animal
Nervous System Diseases Antibodies	>3 publications with FTH1 and Nervous System Diseases
Brain Diseases Antibodies	>3 publications with FTH1 and Brain Diseases
Nerve Degeneration Antibodies	>2 publications with FTH1 and Nerve Degeneration
Neurodegenerative Diseases Antibodies	>2 publications with FTH1 and Neurodegenerative Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with FTH1 and Carcinoma, Hepatocellular
Lung Neoplasms Antibodies	>1 publications with FTH1 and Lung Neoplasms

Organs/Tissues associated with FTH1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>10 publications with FTH1 and Blood
Brain Antibodies	>6 publications with FTH1 and Brain
Liver Antibodies	>5 publications with FTH1 and Liver
Bone Antibodies	>4 publications with FTH1 and Bone
Spleen Antibodies	>3 publications with FTH1 and Spleen
Bone Marrow Antibodies	>3 publications with FTH1 and Bone Marrow
Lung Antibodies	>2 publications with FTH1 and Lung
Eye Antibodies	>2 publications with FTH1 and Eye
Muscle Antibodies	>2 publications with FTH1 and Muscle
Kidney Antibodies	>2 publications with FTH1 and Kidney