Rat KCNJ16 Recombinant Protein – Cat# MBS954996

Inward Rectifier Potassium Channel 16 (KCNJ16) Rat Recombinant Protein

Name: KCNJ16 Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS954996
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS954996

MBS954996 is a recombinant protein targeting Kcnj16. Also known as Recombinant Rat Inward rectifier potassium channel 16 (Kcnj16). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Kcnj16 More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Inward rectifier potassium channel 16 (Kcnj16), Recombinant Protein

Full Product Name

Recombinant Rat Inward rectifier potassium channel 16 (Kcnj16)

Product Gene Name

Kcnj16 recombinant protein

Product Synonym Gene Name

Recombinant Inward rectifier potassium channel 16 (Kcnj16); Inward rectifier potassium channel 16; BIR9 Inward rectifier K(+) channel Kir5.1 Potassium channel, inwardly rectifying subfamily J member 16

Sequence

MSYYGSSYRI VNVDSKYPGY PPEHAIAEKR RARRRLLHKD GSCNVYFKHI FGEWGSYMVD IFTTLVDTKW RHMFVVFSLS YILSWLIFGS IFWLIALHHG DLLSDPDITP CVDNVHSFTA AFLFSLETQT TIGYGYRCVT EECSVAVLTV ILQSILSCII NTFIIGAALA KMATARKRAQ TIRFSYFALI GMRDGKLCLM WRIGDFRPNH VVEGTVRAQL LRYSEDSEGR MTMAFKDLKL VNDQIILVTP VTIVHEIDHE SPLYALDRKA VAKDNFEILV TFIYTGDSTG TSHQSRSSYV PREILWGHRF HDVLEVKRKY YKVNCLQFEG SVEVYAPFCS AKQLDWKDQQ LNNLEKTSPA RGSCTSDTNT RRRSFSAVAM VSSCENPEET SLSPQDECKE VPYQKALLTL NRISMESQM

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

47,936 Da

Sequence Positions

1-419

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 10; NC_005109.3 (99084253..99086022). Location: 10q32.1

3D Structure

ModBase 3D Structure for P52191

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Kcnj16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Kcnj16. It may not necessarily be applicable to this product.

NCBI GI #

13878925

NCBI GeneID

29719

NCBI Accession #

P52191.2

UniProt Primary Accession #

P52191

UniProt Secondary Accession #

Q9JI87

UniProt Related Accession #

P52191

NCBI Official Full Name

Inward rectifier potassium channel 16

NCBI Official Synonym Full Names

potassium inwardly-rectifying channel, subfamily J, member 16

NCBI Official Symbol

Kcnj16

NCBI Official Synonym Symbols

Kir5.1

UniProt Protein Name

Inward rectifier potassium channel 16

UniProt Synonym Protein Names

BIR9; Inward rectifier K(+) channel Kir5.1; Potassium channel, inwardly rectifying subfamily J member 16

Protein Family

Inward rectifier potassium channel

UniProt Gene Name

Kcnj16

UniProt Entry Name

IRK16_RAT

NCBI Protein Information

inward rectifier potassium channel 16; BIR9; inward rectifier K(+) channel Kir5.1; potassium channel, inwardly rectifying subfamily J member 16

NCBI Summary for Kcnj16

inward rectifying potassium channel; may be involved in renal pH regulation [RGD, Feb 2006]

UniProt Comments for Kcnj16

Kir5.1: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ16 subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: protein binding; inward rectifier potassium channel activity

Biological Process: potassium ion import

Research Articles on Kcnj16

1. Heteromeric Kir4.1-Kir5.1 channels confer pH sensitivity to retrotrapezoid nucleus astrocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Kcnj16 recombinant protein

Products by Pathway	Pathway Diagram
Activation Of G Protein Gated Potassium Channels Pathway antibodies	Activation Of G Protein Gated Potassium Channels Pathway Diagram
Activation Of GABAB Receptors Pathway antibodies	Activation Of GABAB Receptors Pathway Diagram
G Protein Gated Potassium Channels Pathway antibodies	G Protein Gated Potassium Channels Pathway Diagram
GABA B Receptor Activation Pathway antibodies	GABA B Receptor Activation Pathway Diagram
GABA Receptor Activation Pathway antibodies	GABA Receptor Activation Pathway Diagram
Gastric Acid Secretion Pathway antibodies	Gastric Acid Secretion Pathway Diagram
Gastric Acid Secretion Pathway antibodies	Gastric Acid Secretion Pathway Diagram
Inhibition Of Voltage Gated Ca2+ Channels Via Gbeta/gamma Subunits Pathway antibodies	Inhibition Of Voltage Gated Ca2+ Channels Via Gbeta/gamma Subunits Pathway Diagram
Inwardly Rectifying K+ Channels Pathway antibodies	Inwardly Rectifying K+ Channels Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram

Organs/Tissues associated with Kcnj16 recombinant protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>4 publications with Kcnj16 and Kidney
Brain Antibodies	>3 publications with Kcnj16 and Brain