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Amyloid-Like Protein 2 (APLP2) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS955186

MBS955186 is a recombinant protein targeting Aplp2. Also known as Recombinant Rat Amyloid-like protein 2 (Aplp2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Amyloid-like protein 2 (Aplp2), Recombinant Protein
Full Product Name
Recombinant Rat Amyloid-like protein 2 (Aplp2)
Product Gene Name
Product Synonym Names
Amyloid-like protein 2; APLP-2; Sperm membrane protein YWK-II
Sequence
GYIEALAAN AGTGFAVAEP QIAMFCGKLN MHVNIQTGKW EPDPTGTKSC LGTKEEVLQY CQEIYPELQI TNVMEANQPV NIDSWCRRDK KQCRSHIVIP FKCLVGEFVS DVLLVPENCQ FFHQERMEVC EKHQRWHTVV KEACLTEGMT LYSYGMLLPC GVDQFHGTEY VCCPQTKVVD SDSTMSKEEE EEEEEDEEED YALDKSEFPT EADLEDFTEA AADEDEDEEE EEEEEGEEVV EDRDYYYDSF KGDDYNEENP TEPSSDGTIS DKEIAHDVKA VCSQEAMTGP CRAVMPRWYF DLSKGKCVRF IYGGCGGNRN NFESEDYCMA VCKTMIPPTP LPTNDVDVYF ETSADDNEHA RFQKAKEQLE IRHRSRMDRV KKEWEEAELQ AKNLPKAERQ TLIQHFQAMV KALEKEAASE KQQLVETHLA RVEAMLNDRR RIALENYLAA LQSDPPRPHR ILQALRRYVR AENKDRLHTI RHYQHVLAVD PEKAAQMKSQ VMTHLHVIEE RRNQSLSLLY KVPYVAQEIQ EEIDELLQEQ RADMDQFTSS ISENPVDVRV SSEESEEIPP FHPFHPFPSL SENEDTQPEL YHPMKKGSGM AEQDGGLIGA EEKVINSKNK MDENMVIDET LDVKEMIFNA ERVGGLEEEP DSVGPLREDF SLSSS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
79,278 Da
Sequence Positions
32-695
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P15943
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Aplp2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Aplp2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Amyloid-like protein 2
UniProt Protein Name
Amyloid-like protein 2
UniProt Synonym Protein Names
Sperm membrane protein YWK-II
Protein Family
UniProt Gene Name
Aplp2
UniProt Synonym Gene Names
APLP-2
UniProt Entry Name
APLP2_RAT

UniProt Comments for Aplp2

APLP2: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. Belongs to the APP family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Cell surface; Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; cell; integral to membrane; nucleus

Molecular Function: serine-type endopeptidase inhibitor activity; heparin binding; identical protein binding; protein binding; transition metal ion binding

Biological Process: cholesterol metabolic process; extracellular matrix organization and biogenesis; cellular copper ion homeostasis; suckling behavior; regulation of protein binding; regulation of epidermal growth factor receptor activity; midbrain development; forebrain development; mating behavior; locomotory behavior; neuromuscular process controlling balance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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