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Stromal Interaction Molecule 2 (STIM2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS956419

MBS956419 is a recombinant protein targeting Stim2. Also known as Recombinant Mouse Stromal interaction molecule 2 (Stim2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Stromal interaction molecule 2 (Stim2), Recombinant Protein
Full Product Name
Recombinant Mouse Stromal interaction molecule 2 (Stim2)
Product Gene Name
Stim2 recombinant protein
Product Synonym Gene Name
Stim2; Kiaa1482
Product Synonym Names
Stromal interaction molecule 2
Sequence
CDLVPR HLRGRRASGS AGAAASPSAA AAGERQALLT DPCMSLSPPC FTEEDRFSLE ALQTIHKQMD DDKDGGIEVD ESDEFIREDM KYKDATNKHS HLHREDKHIT VEDLWKQWKT SEVHNWTLED TLQWLIEFVE LPQYEKNFRD NNVKGTTLPR IAVHETSFMI SQLKISDRSH RQKLQLKALD VVLFGPLTRP PHNWMKDF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
83,925 Da
Sequence Positions
15-218
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P83093
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Stim2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Stim2. It may not necessarily be applicable to this product.

NCBI GI #
281182368
NCBI GeneID
116873
NCBI Accession #
NP_001074572.2
UniProt Primary Accession #
P83093
UniProt Secondary Accession #
Q69ZI3; Q80VF4
UniProt Related Accession #
P83093
GenBank Nucleotide #
NM_001081103.2
NCBI Official Full Name
stromal interaction molecule 2
NCBI Official Synonym Full Names
stromal interaction molecule 2
NCBI Official Symbol
Stim2
UniProt Protein Name
Stromal interaction molecule 2
Protein Family
Stromal interaction molecule
UniProt Gene Name
Stim2
UniProt Synonym Gene Names
Kiaa1482
UniProt Entry Name
STIM2_MOUSE
NCBI Protein Information
stromal interaction molecule 2

UniProt Comments for Stim2

STIM2: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. Oligomer with STIM1. Interacts with ORAI1. Expressed in all tissues and tumor cell lines examined.

Protein type: Membrane protein, integral; Cell adhesion

Cellular Component: membrane; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: protein binding; store-operated calcium channel activity; metal ion binding; calcium channel regulator activity; calcium ion binding

Biological Process: cellular calcium ion homeostasis; activation of store-operated calcium channel activity; transport; calcium ion transport; ion transport; positive regulation of calcium ion transport
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Research Articles on Stim2

1. Stim2 plays a moderate role in the development of autoinmune responses in a murine model of EAE, stimulating the proliferation of lymphocytes and the production of IFN-gamma/IL-17 by neuroantigen-specific T cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Stim2 recombinant protein

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram

Diseases associated with Stim2 recombinant protein

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >6 publications with Stim2 and Disease Models, Animal
 Inflammation Antibodies  >6 publications with Stim2 and Inflammation
 Hyperalgesia Antibodies  >3 publications with Stim2 and Hyperalgesia
 Obesity Antibodies  >1 publications with Stim2 and Obesity
 Cardiomegaly Antibodies  >1 publications with Stim2 and Cardiomegaly
 Abnormalities, Multiple Antibodies  >1 publications with Stim2 and Abnormalities, Multiple
 Fibrosis Antibodies  >1 publications with Stim2 and Fibrosis
 Lymphatic Diseases Antibodies  >1 publications with Stim2 and Lymphatic Diseases
 Neoplasms, Experimental Antibodies  >1 publications with Stim2 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >1 publications with Stim2 and Kidney Diseases

Organs/Tissues associated with Stim2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with Stim2 and Brain
 Kidney Antibodies  >4 publications with Stim2 and Kidney
 Lung Antibodies  >4 publications with Stim2 and Lung
 Embryonic Tissue Antibodies  >3 publications with Stim2 and Embryonic Tissue
 Heart Antibodies  >3 publications with Stim2 and Heart
 Intestine Antibodies  >3 publications with Stim2 and Intestine
 Bone Marrow Antibodies  >3 publications with Stim2 and Bone Marrow
 Lymph Node Antibodies  >2 publications with Stim2 and Lymph Node
 Skin Antibodies  >2 publications with Stim2 and Skin
 Eye Antibodies  >1 publications with Stim2 and Eye
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