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UDP-Glucuronosyltransferase 2b10 (UGT2B10) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS958347

MBS958347 is a recombinant protein targeting UGT2B10. Also known as Recombinant Human UDP-glucuronosyltransferase 2B10 (UGT2B10). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UDP-glucuronosyltransferase 2B10 (UGT2B10), Recombinant Protein
Full Product Name
Recombinant Human UDP-glucuronosyltransferase 2B10 (UGT2B10)
Product Gene Name
UGT2B10 recombinant protein
Product Synonym Gene Name
UGT2B10
Product Synonym Names
Recombinant UDP-glucuronosyltransferase 2B10 (UGT2B10); UDP-glucuronosyltransferase 2B10; UDPGT 2B10 EC= 2.4.1.17
Sequence
KVLVWAAEYS LWMNMKTILK ELVQRGHEVT VLASSASILF DPNDSSTLKL EVYPTSLTKT EFENIIMQLV KRLSEIQKDT FWLPFSQEQE ILWAINDIIR NFCKDVVSNK KLMKKLQESR FDIVFADAYL PCGELLAELF NIPFVYSHSF SPGYSFERHS GGFIFPPSYV PVVMSKLSDQ MTFMERVKNM LYVLYFDFWF QIFNMKKWDQ FYSEVLGRPT TLSETMRKAD IWLMRNSWNF KFPHPFLPNV DFVGGLHCKP AKPLPKEMEE FVQSSGENGV VVFSLGSMVS NMTEERANVI ATALAKIPQK VLWRFDGNKP DALGLNTRLY KWIPQNDLLG HPKTRAFITH GGANGIYEAI YHGIPMVGIP LFFDQPDNIA HMKAKGAAVR VDFNTMSSTD LLNALKTVIN DPSYKENIMK LSRIQHDQPV KPLDRAVFWI EFVMRHKGAK HLRVAAHNLT WFQYHSLDVI GFLLACVATV LFIITKCCLF CFWKFARKGK KGKRD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
60,774 Da
Sequence Positions
24-528
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 4; NC_000004.11 (69681713..69697741). Location: 4q13.2
OMIM
600070
3D Structure
ModBase 3D Structure for P36537
Species
Homo sapiens (Human)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UGT2B10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UGT2B10. It may not necessarily be applicable to this product.

NCBI GI #
4507817
NCBI GeneID
7365
NCBI Accession #
NP_001066.1
UniProt Primary Accession #
P36537
UniProt Secondary Accession #
Q14CR8; A8K9M3
UniProt Related Accession #
P36537
GenBank Nucleotide #
NM_001075.4
NCBI Official Full Name
UDP-glucuronosyltransferase 2B10 isoform 1
NCBI Official Synonym Full Names
UDP glucuronosyltransferase 2 family, polypeptide B10
NCBI Official Symbol
UGT2B10
NCBI Official Synonym Symbols
UDPGT2B10
UniProt Protein Name
UDP-glucuronosyltransferase 2B10
Protein Family
UDP-glucuronosyltransferase
UniProt Gene Name
UGT2B10
UniProt Synonym Gene Names
UDPGT 2B10
UniProt Entry Name
UDB10_HUMAN
NCBI Protein Information
UDP-glucuronosyltransferase 2B10; UDPGT 2B10; UDP glucuronosyltransferase 2B10

UniProt Comments for UGT2B10

UGT2B10: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.

Protein type: Carbohydrate Metabolism - pentose and glucuronate interconversions; Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - ascorbate and aldarate; Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase; Membrane protein, integral; EC 2.4.1.17; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 4q13.2

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; integral to membrane

Molecular Function: glucuronosyltransferase activity

Biological Process: flavonoid biosynthetic process; lipid metabolic process; cellular response to hormone stimulus
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Research Articles on UGT2B10

1. UGT2B17 and UGT2B10 play key roles in the glucuronidation of 3HC in the human liver and that functional polymorphisms in UGT2B17 and UGT2B10 are associated with significantly reduced glucuronidation activities against 3HC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with UGT2B10 recombinant protein

 Products by Pathway  Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway antibodies  Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway Diagram
 Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway antibodies  Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Glucuronidation Pathway antibodies  Glucuronidation Pathway Diagram

Diseases associated with UGT2B10 recombinant protein

 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >2 publications with UGT2B10 and Liver Neoplasms
 Carcinoma Antibodies  >2 publications with UGT2B10 and Carcinoma
 Schizophrenia Antibodies  >1 publications with UGT2B10 and Schizophrenia
 Carcinoma, Squamous Cell Antibodies  >1 publications with UGT2B10 and Carcinoma, Squamous Cell
 Hyperplasia Antibodies  >1 publications with UGT2B10 and Hyperplasia
 Breast Neoplasms Antibodies  >1 publications with UGT2B10 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >1 publications with UGT2B10 and Prostatic Neoplasms
 Gastrointestinal Diseases Antibodies  >1 publications with UGT2B10 and Gastrointestinal Diseases
 Esophageal Neoplasms Antibodies  >1 publications with UGT2B10 and Esophageal Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with UGT2B10 and Carcinoma, Hepatocellular

Organs/Tissues associated with UGT2B10 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >22 publications with UGT2B10 and Liver
 Kidney Antibodies  >5 publications with UGT2B10 and Kidney
 Embryonic Tissue Antibodies  >1 publications with UGT2B10 and Embryonic Tissue
 Mammary Gland Antibodies  >1 publications with UGT2B10 and Mammary Gland
 Connective Tissue Antibodies  >1 publications with UGT2B10 and Connective Tissue
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