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Sodium/Calcium Exchanger 2 (SLC8A2) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS958447

MBS958447 is a recombinant protein targeting Slc8a2. Also known as Recombinant Rat Sodium/calcium exchanger 2 (Slc8a2) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$3925 / 1 mg (E-Coli) +4 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sodium/calcium exchanger 2 (Slc8a2), Recombinant Protein
Full Product Name
Recombinant Rat Sodium/calcium exchanger 2 (Slc8a2) , partial
Product Gene Name
Slc8a2 recombinant protein
Sequence
EATPTPSLPP PPANDSDASP GGCQGSYRCQ PGVLLPVWEP DDPSLGDKAA RAVVYFVAMV YMFLGLSIIA DRFMASIEVI TSKEKEITIT KANGETSVGT VRIWNETVSN LTLMALGSSA PEILLSVIEV CGHNFQAGEL GPGTIVGSAA FNMFVVIAVC VYVIPAGESR KIKHLRVFFV TASWSIFAYV WLYLILAVFS PGVVQVWEAL LTLVFFPVCV VFAWMADKRL LFYKYVYKRY RTDPRSGIII GAEGDPPKSI ELDGTFVGTE VPGELGALGT GPAEARELDA SRREVIQILK DLKQKHPDKD LEQLVGIAKY YALLHQQKSR AFYRIQATRL MTGAGNVLRR HAADAARRPG ANDGAPDDED DGASRIFFEP SLYHCLENCG SVLLSVACQG GEGNSTFYVD YRTEDGSAKA GSDYEYSEGT LVFKPGETQK ELRIGIIDDD IFEEDEHFFV RLLNLRVGDA QGMFEPDGGG RPKGRLVAPL LATVTILDDD HAGIFSFQDR LLHVSECMGT VDVRVVRSSG ARGTVRLPYR TVDGTARGGG VHYEDACGEL EFGDDETMKT LQVKIVDDEE YEKKDNFFIE LGQPQWLKRG ISALLLNQGD GDRKLTAEEE EAQRIAEMGK PVLGENCRLE VIIEESYDFK NTVDKLIKKT NLALVIGTHS WREQFLEAVT VSAGDEEEDE DGSREERLPS CFDYVMHFLT VFWKVLFACL PPTEYCHGWA CFGVCILVIG LLTALIGDLA SHFGCTVGLK DSVNAVVFVA LGTSIPDTFA SKVAALQDQC ADASIGNVTG SNAVNVFLGL GVAWSVAAVY WAVQGRPFEV RTGTLAFSVT LFTVFAFVGI AVLLYRRRPH IGGELGGPRG PKLATTALFL GLWFLYILFA SLEAYCHIRG F
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
100,523 Da
Sequence Positions
21-921
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P48768
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Slc8a2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Slc8a2. It may not necessarily be applicable to this product.

NCBI GI #
17530967
NCBI GeneID
140447
NCBI Accession #
NP_511174.1
UniProt Primary Accession #
P48768
UniProt Related Accession #
P48768
GenBank Nucleotide #
NM_078619.1
NCBI Official Full Name
sodium/calcium exchanger 2
NCBI Official Synonym Full Names
solute carrier family 8 member A2
NCBI Official Symbol
Slc8a2
NCBI Official Synonym Symbols
Ncx2
UniProt Protein Name
Sodium/calcium exchanger 2
UniProt Synonym Protein Names
Na(+)/Ca(2+)-exchange protein 2; Solute carrier family 8 member 2
Protein Family
Sodium/calcium exchanger
UniProt Gene Name
Slc8a2
UniProt Synonym Gene Names
Ncx2
NCBI Protein Information
sodium/calcium exchanger 2

NCBI Summary for Slc8a2

isoform 2 of sodium/calcium exchanger; regulates intracellular calcium levels and maintains calcium homeostasis; may be important for the control of synaptic plasticity [RGD, Feb 2006]

UniProt Comments for Slc8a2

Mediates the electrogenic exchange of Ca2+ against Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes (PubMed:8021246, PubMed:9486131). Contributes to cellular Ca2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca2+ and Na+ excretion.
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Research Articles on Slc8a2

1. analyze the equilibrium and kinetic properties of Ca(2+) binding to purified preparations of CBD1, CBD2, and CBD12 from NCX2 and from NCX3 splice variants

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Slc8a2 recombinant protein

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Calcium Homeostasis Pathway antibodies  Platelet Calcium Homeostasis Pathway Diagram
 Platelet Homeostasis Pathway antibodies  Platelet Homeostasis Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Reduction Of Cytosolic Ca++ Levels Pathway antibodies  Reduction Of Cytosolic Ca++ Levels Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Sodium/Calcium Exchangers Pathway antibodies  Sodium/Calcium Exchangers Pathway Diagram

Diseases associated with Slc8a2 recombinant protein

 Disease Name  Pubmed Publications
 Brain Ischemia Antibodies  >7 publications with Slc8a2 and Brain Ischemia
 Stroke Antibodies  >5 publications with Slc8a2 and Stroke
 Neoplasms Antibodies  >3 publications with Slc8a2 and Neoplasms
 Drug Toxicity Antibodies  >2 publications with Slc8a2 and Drug Toxicity
 Pain Antibodies  >1 publications with Slc8a2 and Pain
 Neurologic Manifestations Antibodies  >1 publications with Slc8a2 and Neurologic Manifestations
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