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Cadherin-11 (CDH11) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966286

MBS966286 is a recombinant protein targeting CDH11. Also known as Recombinant Human Cadherin-11 (CDH11). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1850 / 0.5 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cadherin-11 (CDH11), Recombinant Protein
Full Product Name
Recombinant Human Cadherin-11 (CDH11)
Product Gene Name
Product Synonym Names
Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
Sequence
GWVWNQFFVI EEYTGPDPVL VGRLHSDIDS GDGNIKYILS GEGAGTIFVI DDKSGNIHAT KTLDREERAQ YTLMAQAVDR DTNRPLEPPS EFIVKVQDIN DNPPEFLHET YHANVPERSN VGTSVIQVTA SDADDPTYGN SAKLVYSILE GQPYFSVEAQ TGIIRTALPN MDREAKEEYH VVIQAKDMGG HMGGLSGTTK VTITLTDVND NPPKFPQSVY QMSVSEAAVP GEEVGRVKAK DPDIGENGLV TYNIVDGDGM ESFEITTDYE TQEGVIKLKK PVDFETKRAY SLKVEAANVH IDPKFISNGP FKDTVTVKIS VEDADEPPMF LAPSYIHEVQ ENAAAGTVVG RVHAKDPDAA NSPIRYSIDR HTDLDRFFTI NPEDGFIKTT KPLDREETAW LNITVFAAEI HNRHQEAKVP VAIRVLDVND NAPKFAAPYE GFICESDQTK PLSNQPIVTI SADDKDDTAN GPRFIFSLPP EIIHNPNFTV RDNRDNTAGV YARRGGFSRQ KQDLYLLPIV ISDGGIPPMS STNTLTIKVC GCDVNGALLS CNAEAYILNA GLST
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
76,457 Da
Sequence Positions
54-617, Provide the complete extracellular domain.
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
600023
3D Structure
ModBase 3D Structure for P55287
Species
Homo sapiens (Human)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CDH11 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDH11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cadherin-11 preproprotein
NCBI Official Synonym Full Names
cadherin 11, type 2, OB-cadherin (osteoblast)
NCBI Official Symbol
CDH11
NCBI Official Synonym Symbols
OB; CAD11; CDHOB; OSF-4
UniProt Protein Name
Cadherin-11
UniProt Synonym Protein Names
OSF-4; Osteoblast cadherin; OB-cadherin
Protein Family
UniProt Gene Name
CDH11
UniProt Synonym Gene Names
OB-cadherin
UniProt Entry Name
CAD11_HUMAN
NCBI Protein Information
cadherin-11

NCBI Summary for CDH11

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
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UniProt Comments for CDH11

CDH11: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with PCDH8. Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16q21

Cellular Component: cytoplasm; plasma membrane; integral to membrane

Molecular Function: calcium ion binding

Biological Process: intercellular junction assembly and maintenance; ossification; cell adhesion; homophilic cell adhesion; corticospinal tract morphogenesis; skeletal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDH11 recombinant protein

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