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Serine Hydroxymethyltransferase, Cytosolic (SHMT1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966664

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one… More details

$1265 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine hydroxymethyltransferase, cytosolic (SHMT1), Recombinant Protein
Full Product Name
Recombinant Human Serine hydroxymethyltransferase, cytosolic (SHMT1)
Product Gene Name
Sequence
TMPVNGAHKD ADLWSSHDKM LAQPLKDSDV EVYNIIKKES NRQRVGLELI ASENFASRAV LEALGSCLNN KYSEGYPGQR YYGGTEFIDE LETLCQKRAL QAYKLDPQCW GVNVQPYSGS PANFAVYTAL VEPHGRIMGL DLPDGGHLTH GFMTDKKKIS ATSIFFESMP YKVNPDTGYI NYDQLEENAR LFHPKLIIAG TSCYSRNLEY ARLRKIADEN GAYLMADMAH ISGLVAAGVV PSPFEHCHVV TTTTHKTLRG CRAGMIFYRK GVKSVDPKTG KEILYNLESL INSAVFPGLQ GGPHNHAIAG VAVALKQAMT LEFKVYQHQV VANCRALSEA LTELGYKIVT GGSDNHLILV DLRSKGTDGG RAEKVLEACS IACNKNTCPG DRSALRPSGL RLGTPALTSR GLLEKDFQKV AHFIHRGIEL TLQIQSDTGV RATLKEFKER LAGDKYQAAV QALREEVESF ASLFPLPGLP DF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
37,672 Da
Sequence Positions
2-483, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
182144
3D Structure
ModBase 3D Structure for P34896
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SHMT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SHMT1 purchase

MBS966664 is a recombinant protein targeting SHMT1. Also known as Recombinant Human Serine hydroxymethyltransferase, cytosolic (SHMT1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for SHMT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine hydroxymethyltransferase, cytosolic isoform 3
NCBI Official Synonym Full Names
serine hydroxymethyltransferase 1
NCBI Official Symbol
SHMT1
NCBI Official Synonym Symbols
SHMT; CSHMT
UniProt Protein Name
Serine hydroxymethyltransferase, cytosolic
UniProt Synonym Protein Names
Glycine hydroxymethyltransferase; Serine methylase
UniProt Gene Name
SHMT1
UniProt Synonym Gene Names
SHMT
NCBI Protein Information
serine hydroxymethyltransferase, cytosolic

NCBI Summary for SHMT1

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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UniProt Comments for SHMT1

Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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