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CA8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968840

MBS968840 is an antibody targeting CA8. Also known as CA8 Antibody. Reactive in Human, Mouse. Host: Rabbit. Does not have a carbonic anhydrase catalytic activity. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CA8, Polyclonal Antibody
Full Product Name
CA8 Antibody
Product Gene Name
Product Synonym Names
CARP; Carbonic anhydrase VIII; CA8; CALS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
32,973 Da
OMIM
114815
3D Structure
ModBase 3D Structure for P35219
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Carbonic anhydrase-related protein (1-290aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54705 / sc-54706 / sc-67330
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CA8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CA8 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-CA8 antibody

Western blot
All lanes: CA8 antibody at 8ug/ml+mouse liver tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 33kDa
Observed band size: 33kDa
Rabbit Anti-CA8 Polyclonal Antibody – Cat# MBS968840

Immunohistochemistry (IHC) of anti-CA8 antibody

Immunohistochemistry of paraffin-embedded human brain tissue using MBS968840 at dilution 1:100
Rabbit Anti-CA8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS968840

Immunohistochemistry (IHC) of anti-CA8 antibody

Immunohistochemistry of paraffin-embedded human breast cancer tissue using MBS968840 at dilution 1:100
Rabbit Anti-CA8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS968840

Other Notes

Small volumes of anti-CA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CA8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carbonic anhydrase-related protein
NCBI Official Synonym Full Names
carbonic anhydrase VIII
NCBI Official Symbol
CA8
NCBI Official Synonym Symbols
CALS; CARP; CAMRQ3; CA-VIII
UniProt Protein Name
Carbonic anhydrase-related protein
UniProt Synonym Protein Names
Carbonic anhydrase VIII; CA-VIII
UniProt Gene Name
CA8
UniProt Synonym Gene Names
CALS; CARP; CA-VIII
UniProt Entry Name
CAH8_HUMAN
NCBI Protein Information
carbonic anhydrase-related protein

NCBI Summary for CA8

The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq, Jul 2008]
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UniProt Comments for CA8

CA8: Does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3). CMARQ3 is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation. Belongs to the alpha-carbonic anhydrase family.

Protein type: Lyase; Energy Metabolism - nitrogen

Chromosomal Location of Human Ortholog: 8q12.1

Cellular Component: cytoplasm

Molecular Function: carbonate dehydratase activity; protein binding; zinc ion binding

Biological Process: one-carbon compound metabolic process; phosphoinositide-mediated signaling

Disease: Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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