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FARP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968881

Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation,… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FARP2, Polyclonal Antibody
Full Product Name
FARP2 Antibody
Product Gene Name
anti-FARP2 antibody
Product Synonym Names
FERM; RhoGEF and pleckstrin domain-containing protein 2; FARP2; KIAA0793; PLEKHC3; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: FARP2 (MBS968881)
FITC Conjugated Antibody: FARP2 (MBS1493246)
Matching Pairs
Unconjugated Antibody: FARP2 (MBS968881)
HRP Conjugated Antibody: FARP2 (MBS1494522)
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Molecular Weight
72,263 Da
3D Structure
ModBase 3D Structure for O94887
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human FERM, RhoGEF and pleckstrin domain-containing protein 2 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-167842
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FARP2 antibody
ELISA (EIA), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-FARP2 antibody

Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS968881 at dilution of 1:100
Rabbit Anti-FARP2 Polyclonal Antibody – Cat# MBS968881

Immunohistochemistry (IHC) of anti-FARP2 antibody

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS968881 at dilution of 1:100
Rabbit Anti-FARP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS968881

Immunohistochemistry (IHC) of anti-FARP2 antibody

Immunofluorescent analysis of Hela cells using MBS968881 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-FARP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS968881

Other Notes

Small volumes of anti-FARP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FARP2 purchase

MBS968881 is an antibody targeting FARP2. Also known as FARP2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FARP2. It may not necessarily be applicable to this product.

NCBI GI #
545478372
NCBI GeneID
9855
NCBI Accession #
NP_001269912.1
UniProt Primary Accession #
O94887
UniProt Secondary Accession #
Q53QM5; Q8WU27; Q9UFE7; B7Z6J8; F5GZ84
UniProt Related Accession #
O94887
GenBank Nucleotide #
NM_001282983.1
NCBI Official Full Name
FERM, RhoGEF and pleckstrin domain-containing protein 2 isoform b
NCBI Official Synonym Full Names
FERM, ARH/RhoGEF and pleckstrin domain protein 2
NCBI Official Symbol
FARP2
NCBI Official Synonym Symbols
FIR; FRG; PLEKHC3
UniProt Protein Name
FERM, RhoGEF and pleckstrin domain-containing protein 2
UniProt Synonym Protein Names
FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3
Protein Family
FERM, RhoGEF and pleckstrin domain-containing protein
UniProt Gene Name
FARP2
UniProt Synonym Gene Names
KIAA0793; PLEKHC3; FIR; PH domain-containing family C member 3
UniProt Entry Name
FARP2_HUMAN
NCBI Protein Information
FERM, RhoGEF and pleckstrin domain-containing protein 2

UniProt Comments for FARP2

FARP2: Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; Motility/polarity/chemotaxis; Cell development/differentiation; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoplasm; cytoskeleton; cytosol; extrinsic to membrane

Molecular Function: cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity

Biological Process: actin cytoskeleton reorganization; axon guidance; cell adhesion; neuron remodeling; osteoclast differentiation; positive regulation of GTPase activity; Rac protein signal transduction; regulation of integrin activation; regulation of Rho protein signal transduction
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Research Articles on FARP2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FARP2 antibody

 Reference Product  PubMed Publications
 RAC1 antibody  >5 publications with FARP2 and RAC1
 CDC42 antibody  >3 publications with FARP2 and CDC42
 SEMA3A antibody  >2 publications with FARP2 and SEMA3A
 PLXNA4 antibody  >1 publications with FARP2 and PLXNA4
 PLXNA1 antibody  >1 publications with FARP2 and PLXNA1

Pathways associated with anti-FARP2 antibody

 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Nectin Adhesion Pathway antibodies  Nectin Adhesion Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Regulation Of CDC42 Activity Pathway antibodies  Regulation Of CDC42 Activity Pathway Diagram
 SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway antibodies  SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway Diagram

Diseases associated with anti-FARP2 antibody

 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >3 publications with FARP2 and Mental Disorders
 Neurobehavioral Manifestations Antibodies  >2 publications with FARP2 and Neurobehavioral Manifestations
 Autistic Disorder Antibodies  >2 publications with FARP2 and Autistic Disorder
 Disease Models, Animal Antibodies  >1 publications with FARP2 and Disease Models, Animal
 Leukemia, Lymphocytic, Chronic, B-Cell Antibodies  >1 publications with FARP2 and Leukemia, Lymphocytic, Chronic, B-Cell
 Chromosome 2q37 deletion syndrome Antibodies  >1 publications with FARP2 and Chromosome 2q37 deletion syndrome

Organs/Tissues associated with anti-FARP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with FARP2 and Brain
 Embryonic Tissue Antibodies  >3 publications with FARP2 and Embryonic Tissue
 Nerve Antibodies  >3 publications with FARP2 and Nerve
 Bone Antibodies  >2 publications with FARP2 and Bone
 Ovary Antibodies  >2 publications with FARP2 and Ovary
 Thymus Antibodies  >1 publications with FARP2 and Thymus
 Pancreas Antibodies  >1 publications with FARP2 and Pancreas
 Kidney Antibodies  >1 publications with FARP2 and Kidney
 Muscle Antibodies  >1 publications with FARP2 and Muscle
 Lung Antibodies  >1 publications with FARP2 and Lung
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