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CCDC98 Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9632058

MBS9632058 is a blocking peptide targeting ABRAXAS1. Also known as CCDC98 Blocking Peptide. More details

$460 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCDC98 (ABRAXAS1), Blocking Peptide
Full Product Name
CCDC98 Blocking Peptide
Product Gene Name
ABRAXAS1 blocking peptide
Product Synonym Names
3830405G04Rik; 5630400M01Rik; ABRA1; ABRAXAS; Abraxas protein; AI506069; AL024423; AV118690; BRCA1-A complex subunit Abraxas; coiled coil domain containing 98; Coiled-coil domain-containing protein 98; F175A_HUMAN; FAM175A; Family with sequence similarity
Antibody/Peptide Pairs
ABRAXAS1 peptide (MBS9632058) is used for blocking the activity of ABRAXAS1 antibody (MBS9629675)
Molecular Weight
409
OMIM
phenotype 611143
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ABRAXAS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ABRAXAS1. It may not necessarily be applicable to this product.

NCBI GI #
126215684
NCBI GeneID
84142
NCBI Accession #
Q6UWZ7.2
UniProt Primary Accession #
Q6UWZ7
UniProt Secondary Accession #
Q9H8I1; Q9H9N4; A5JJ07
UniProt Related Accession #
Q6UWZ7
NCBI Official Full Name
BRCA1-A complex subunit Abraxas
NCBI Official Synonym Full Names
family with sequence similarity 175, member A
NCBI Official Symbol
FAM175A
NCBI Official Synonym Symbols
ABRA1; CCDC98
UniProt Protein Name
BRCA1-A complex subunit Abraxas
UniProt Synonym Protein Names
Coiled-coil domain-containing protein 98; Protein FAM175A
UniProt Gene Name
FAM175A
UniProt Synonym Gene Names
ABRA1; CCDC98
UniProt Entry Name
F175A_HUMAN
NCBI Protein Information
BRCA1-A complex subunit Abraxas; abraxas protein; coiled-coil domain containing 98; coiled-coil domain-containing protein 98

UniProt Comments for ABRAXAS1

Abraxas: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1. Belongs to the FAM175 family. Abraxas subfamily.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: nucleus

Molecular Function: protein binding; polyubiquitin binding

Biological Process: positive regulation of DNA repair; double-strand break repair; chromatin modification; response to ionizing radiation; G2/M transition DNA damage checkpoint
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Research Articles on ABRAXAS1

1. The recurrent Abraxas c.1082G>A mutation connects to breast cancer predisposition.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ABRAXAS1 blocking peptide

 Reference Product  PubMed Publications
 BRCA1 blocking peptide  >23 publications with ABRAXAS1 and BRCA1
 BRCC3 blocking peptide  >6 publications with ABRAXAS1 and BRCC3
 BRE blocking peptide  >4 publications with ABRAXAS1 and BRE
 BARD1 blocking peptide  >3 publications with ABRAXAS1 and BARD1
 ATM blocking peptide  >2 publications with ABRAXAS1 and ATM
 MRE11A blocking peptide  >2 publications with ABRAXAS1 and MRE11A
 RAD50 blocking peptide  >1 publications with ABRAXAS1 and RAD50
 UIMC1 blocking peptide  >1 publications with ABRAXAS1 and UIMC1

Diseases associated with ABRAXAS1 blocking peptide

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >7 publications with ABRAXAS1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >5 publications with ABRAXAS1 and Ovarian Neoplasms

Organs/Tissues associated with ABRAXAS1 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with ABRAXAS1 and Lung
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