Rat CPB1 Active Protein – Cat# MBS691474

Carboxypeptidase-B (CPB1) Rat Active Protein

Name: CPB1 Active Protein; Carboxypeptidase-B; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS691474
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691474

Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific… More details

$305 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carboxypeptidase-B (Cpb1), Active Protein

Full Product Name

Rat Carboxypeptidase-B

Product Gene Name

Cpb1 active protein

Product Synonym Names

Cpb1; Cpb

Sequence

ASGHSYTKYN NWETIEAWIQ QVATDNPDLV TQSVIGTTFE GRNMYVLK IG KTRPNKPAIF IDCGFHAREW ISPAFCQWFV REAVRTYN QE IHMKQLLDEL DFYVLPVVNI DGYVYTWTKD RMWRKTRS TM AGSSCLGVDP NRNFNAGWCE VGASRSPCSE TYCGPAPE SE KETKALADFI RNNLSTIKAY LTIHSYSQMM LYPYSYDY KL PENYEELNAL VKGAAKELAT LHGTKYTYGP GATTIYPA AG GSDDWSYDQG IKYSFTFELR DTGFFGFLLP ESQIRQTC EE TMLAVKYIAN YVREHLY

Host

E. coli

Form/Format

Lyophilized (20mM Tris, pH 8.0 + 50mM NaCl)

Purity/Purification

>95% by SDS-PAGE & HPLC analysis

Preparation and Storage

The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

Molecular Weight

47,515 Da

Chromosome Location

Chromosome: 2; NC_005101.3 (124787804..124850792, complement). Location: 2q24

3D Structure

ModBase 3D Structure for P19223

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin level

< 0.1 ng /ug of protein (<1EU/ug).

Length (aa)

307

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer (e.g. PBS) containing a carrier protein (e.g. 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Biological Activity

Carboxypeptidase-B sequentially cleaves C terminal K and R residues.

Product Categories/Family for Cpb1 active protein

Cytokines & Growth Factors

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of Cpb1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cpb1 purchase

MBS691474 is an active protein targeting Cpb1. Also known as Rat Carboxypeptidase-B. Host: E. coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Cpb1. It may not necessarily be applicable to this product.

NCBI GI #

6978697

NCBI GeneID

24271

NCBI Accession #

NP_036665.1

UniProt Primary Accession #

P19223

UniProt Related Accession #

P19223

GenBank Nucleotide #

NM_012533.1

NCBI Official Full Name

carboxypeptidase B

NCBI Official Synonym Full Names

carboxypeptidase B1 (tissue)

NCBI Official Symbol

Cpb1

NCBI Official Synonym Symbols

Cpb

UniProt Protein Name

Carboxypeptidase B

Protein Family

Carboxypeptidase

UniProt Gene Name

Cpb1

UniProt Synonym Gene Names

Cpb

UniProt Entry Name

CBPB1_RAT

NCBI Protein Information

carboxypeptidase B; pancreatic carboxypeptidase B1

NCBI Summary for Cpb1

putative carboxypeptidase B protein [RGD, Feb 2006]

UniProt Comments for Cpb1

Catalytic activity: Preferential release of a C-terminal lysine or arginine amino acid.

Cofactor: Binds 1 zinc ion per subunit

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the peptidase M14 family.

Research Articles on Cpb1

1. Mutants C383G, C383A had higher k(cat)/K(m) values which indicated increased catalytic abilities. And both had higher thermal stability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Cpb1 active protein

Reference Product	PubMed Publications
Cpa1 active protein	>3 publications with Cpb1 and Cpa1
Cpe active protein	>2 publications with Cpb1 and Cpe
Ctrc active protein	>1 publications with Cpb1 and Ctrc

Pathways associated with Cpb1 active protein

Products by Pathway	Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram

Diseases associated with Cpb1 active protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with Cpb1 and Neoplasms
Immune System Diseases Antibodies	>2 publications with Cpb1 and Immune System Diseases
Inflammation Antibodies	>2 publications with Cpb1 and Inflammation
Chromosome Aberrations Antibodies	>1 publications with Cpb1 and Chromosome Aberrations
Death Antibodies	>1 publications with Cpb1 and Death
Kidney Diseases Antibodies	>1 publications with Cpb1 and Kidney Diseases
Liver Diseases Antibodies	>1 publications with Cpb1 and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with Cpb1 and Liver Neoplasms
Liver Neoplasms, Experimental Antibodies	>1 publications with Cpb1 and Liver Neoplasms, Experimental
Carcinoma Antibodies	>1 publications with Cpb1 and Carcinoma

Organs/Tissues associated with Cpb1 active protein

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>18 publications with Cpb1 and Pancreas