• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Complement Factor B (CFB) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2153524

MBS2153524 is an active protein targeting CFB. Also known as Active Complement Factor B (CFB). Host: E coli. More details

$285 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Complement Factor B (CFB), Active Protein
Full Product Name
Active Complement Factor B (CFB)
Product Gene Name
CFB active protein
Product Synonym Names
Complement Factor B; CFB active protein (prokaryotic), Mouse; CF-B; BF; BFD; CFAB; GBG; H2-Bf; PBF2; B-Factor; Properdin; Properdin factor B; C3/C5 convertase; Glycine-rich beta glycoprotein
Host
E coli
Form/Format
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Freeze-dried powder
Purity/Purification
Greater than 90% by SDS-PAGE
Preparation and Storage
Store at 2-8 degree C for one month, -80 degree C for 12 months
Stable for 12 months if correctly stored.
Molecular Weight
85,004 Da
Sequence Positions
Thr25~Arg258
Chromosome Location
Chromosome: 17; NC_000083.6 (34856374..34862514, complement). Location: 17 B1; 17 18.41 cM
3D Structure
ModBase 3D Structure for P04186
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Expression System
Prokaryotic expression
Species
Mouse
Tag
N-terminal His
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Isoelectric Point
5.1
Research Area
Infection immunity

Product Categories/Family for CFB active protein

Active proteins
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for CFB active protein
Cell culture, Activity Assay

SDS-PAGE of CFB active protein

Figure. SDS-PAGE
CFB Active Protein – Cat# MBS2153524

Activity of CFB active protein

Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 converta
CFB Active Protein, Activity – Cat# MBS2153524

Other Notes

Small volumes of CFB active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CFB. It may not necessarily be applicable to this product.

NCBI GI #
192414
NCBI GeneID
14962
NCBI Accession #
AAA63293.1
UniProt Primary Accession #
P04186
UniProt Related Accession #
P04186
NCBI Official Full Name
factor B
NCBI Official Synonym Full Names
complement factor B
NCBI Official Symbol
Cfb
NCBI Official Synonym Symbols
B; Bf; C2; Fb; H2-Bf; AI195813; AI255840
UniProt Protein Name
Complement factor B
UniProt Synonym Protein Names
C3/C5 convertase
Protein Family
Complement factor
UniProt Gene Name
Cfb
UniProt Synonym Gene Names
Bf; H2-Bf
UniProt Entry Name
CFAB_MOUSE
NCBI Protein Information
complement factor B; Factor B; properdin; C3/C5 convertase; complement component 2 (within H-2S); alternative-complement pathway C3/C5 convertase; histocompatibility 2, complement component factor B

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CFB active protein

 Reference Product  PubMed Publications
 Cfh active protein  >85 publications with CFB and Cfh
 Cfhr1 active protein  >10 publications with CFB and Cfhr1
 Cfd active protein  >4 publications with CFB and Cfd
 Cd55 active protein  >2 publications with CFB and Cd55
 Ifng active protein  >1 publications with CFB and Ifng

Pathways associated with CFB active protein

 Products by Pathway  Pathway Diagram
 Activation Of C3 And C5 Pathway antibodies  Activation Of C3 And C5 Pathway Diagram
 Alternative Complement Activation Pathway antibodies  Alternative Complement Activation Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Regulation Of Complement Cascade Pathway antibodies  Regulation Of Complement Cascade Pathway Diagram

Organs/Tissues associated with CFB active protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >28 publications with CFB and Muscle
 Liver Antibodies  >23 publications with CFB and Liver
 Joint Antibodies  >17 publications with CFB and Joint
 Kidney Antibodies  >14 publications with CFB and Kidney
 Intestine Antibodies  >13 publications with CFB and Intestine
 Skin Antibodies  >9 publications with CFB and Skin
 Brain Antibodies  >8 publications with CFB and Brain
 Lung Antibodies  >7 publications with CFB and Lung
 Connective Tissue Antibodies  >4 publications with CFB and Connective Tissue
 Molar Antibodies  >4 publications with CFB and Molar
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000