CXCL16 Active Protein

Name: CXCL16 Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650195
Price: 440 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650195

CXCL16 is a recently discovered alpha chemokine (CXC) which also has characteristics of CC chemokines and a structure similar to Fractalkine. It may also play a role in attracting activated lymphocyte subsets during in ammation and may assist immune… More details

$440 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CXCL16, Active Protein

Full Product Name

CXCL16, Mouse, Recombinant

Product Gene Name

CXCL16 active protein

Sequence

NQGSVAGSCD RTISSGTQIP QGTLDHIRKY LKAFHRCPFF IRFQLQSKSV CGGSQDQWVR ELVDCFERKE CGTGHGKSFH HQKHLP

Host

E Coli

Form/Format

The sterile ltered solution was lyophilized from 10mM HoAc.

Purity/Purification

Highly Purified
98% by SDS-PAGE and HPLC analyses

Preparation and Storage

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 degree C. Reconstituted murine CXCL16 should be stored in working aliquots at -20 degree C.

Molecular Weight

9.9kDa

Chromosome Location

Chromosome: 17; NC_000017.10 (4636828..4643223, complement). Location: 17p13

OMIM

605398

3D Structure

ModBase 3D Structure for Q9H2A7

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Determined by its ability to chemoattract murine lymphocytes using a concentration of 20-1000ng/ml.

Country of Origin

USA

Endotoxin Level

0.1ng/ug (1EU/ug)

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other buffers and stored at 4 degree C for 1 week or stored at -20 degree C for future use.

Product Categories/Family for CXCL16 active protein

Growth Factors; Cytokines; Growth Factors-CXCL

Other Notes

Small volumes of CXCL16 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL16 purchase

MBS650195 is an active protein targeting CXCL16. Also known as CXCL16, Mouse, Recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL16. It may not necessarily be applicable to this product.

NCBI GI #

154816178

NCBI GeneID

58191

NCBI Accession #

NP_001094282.1

UniProt Primary Accession #

Q9H2A7

UniProt Secondary Accession #

Q8TC80; Q96K63; Q9BXD6; Q9H2F6; A0N0N4; A8K7U9; B2RCB0

UniProt Related Accession #

Q9H2A7

GenBank Nucleotide #

NM_001100812.1

NCBI Official Full Name

C-X-C motif chemokine 16

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 16

NCBI Official Symbol

CXCL16

NCBI Official Synonym Symbols

SRPSOX; CXCLG16; SR-PSOX

UniProt Protein Name

C-X-C motif chemokine 16

UniProt Synonym Protein Names

Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16

Protein Family

C-X-C motif chemokine

UniProt Gene Name

CXCL16

UniProt Synonym Gene Names

SCYB16; SRPSOX

UniProt Entry Name

CXL16_HUMAN

NCBI Protein Information

C-X-C motif chemokine 16; OTTHUMP00000115953; CXC chemokine ligand 16; small-inducible cytokine B16; transmembrane chemokine CXCL16; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein

UniProt Comments for CXCL16

Function: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis

By similarity. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Subcellular location: Cell membrane; Single-pass type I membrane protein

Potential. Secreted. Note: Also exists as a soluble form.

Tissue specificity: Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

Post-translational modification: Glycosylated.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Sequence caution: The sequence AAG34365.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH17588.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH44930.1 differs from that shown. Reason: Erroneous initiation. The sequence ABK41925.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB55078.1 differs from that shown. Reason: Erroneous initiation. The sequence BAF84803.1 differs from that shown. Reason: Erroneous initiation. The sequence BAG37507.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on CXCL16

1. High CXCL16/CXCR6 expression may be related to aggressive cancer behavior, and high CXCL16 expression to bone metastases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CXCL16 active protein

Reference Product	PubMed Publications
CXCR6 active protein	>93 publications with CXCL16 and CXCR6

Pathways associated with CXCL16 active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with CXCL16 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>54 publications with CXCL16 and Inflammation
Neoplasms Antibodies	>36 publications with CXCL16 and Neoplasms
Kidney Diseases Antibodies	>15 publications with CXCL16 and Kidney Diseases
Genital Diseases, Male Antibodies	>9 publications with CXCL16 and Genital Diseases, Male
Myocardial Infarction Antibodies	>9 publications with CXCL16 and Myocardial Infarction
Arthritis, Rheumatoid Antibodies	>9 publications with CXCL16 and Arthritis, Rheumatoid
Intestinal Diseases Antibodies	>8 publications with CXCL16 and Intestinal Diseases
Prostatic Diseases Antibodies	>8 publications with CXCL16 and Prostatic Diseases
Fibrosis Antibodies	>8 publications with CXCL16 and Fibrosis
Neoplasm Metastasis Antibodies	>7 publications with CXCL16 and Neoplasm Metastasis

Organs/Tissues associated with CXCL16 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>120 publications with CXCL16 and Blood
Muscle Antibodies	>23 publications with CXCL16 and Muscle
Liver Antibodies	>22 publications with CXCL16 and Liver
Lung Antibodies	>19 publications with CXCL16 and Lung
Kidney Antibodies	>16 publications with CXCL16 and Kidney
Bone Antibodies	>15 publications with CXCL16 and Bone
Brain Antibodies	>10 publications with CXCL16 and Brain
Prostate Antibodies	>8 publications with CXCL16 and Prostate
Lymph Node Antibodies	>8 publications with CXCL16 and Lymph Node
Placenta Antibodies	>4 publications with CXCL16 and Placenta