DUSP23 Active Protein

Name: DUSP23 Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS845279
Price: 570 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845279

Background: DuSP23, also known as low molecular mass dual specificity phosphatase 3(LDP-3), belongs to the protein-tyrosine phosphatase family. This protein is a protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

DUSP23, Active Protein

Full Product Name

DUSP23, human recombinant

Product Gene Name

DUSP23 active protein

Product Synonym Names

Dual specificity protein phosphatase 23; DUSP25; LDP-3; MOSP; VHZ

Sequence

MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK

Host

E Coli

Form/Format

1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 100 mM NaCl and 2 mM DTT
Appearance: Liquid

Purity/Purification

>=90%

Concentration

1 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

18.8 kDa (170 aa, 1-150 aa + His Tag)

3D Structure

ModBase 3D Structure for Q9BVJ7

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Specific activity is > 320 unit/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1 nmole of p-nitrophenyl phosphate (pNPP) per minute at 37 degree C, pH7.5 using 10 mM of substrate.

Results

Specific activity is > 320 unit/mg

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for DUSP23 active protein

Proteins and Enzymes; Proteins and Enzymes (A-Z)

Applications Tested/Suitable for DUSP23 active protein

SDS-PAGE

Other Notes

Small volumes of DUSP23 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DUSP23 purchase

MBS845279 is an active protein targeting DUSP23. Also known as DUSP23, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP23. It may not necessarily be applicable to this product.

NCBI GI #

56786144

NCBI GeneID

54935

NCBI Accession #

NP_060293.2

UniProt Primary Accession #

Q9BVJ7

UniProt Secondary Accession #

Q9NX48

UniProt Related Accession #

Q9BVJ7

GenBank Nucleotide #

NM_017823.3

NCBI Official Full Name

dual specificity protein phosphatase 23

NCBI Official Synonym Full Names

dual specificity phosphatase 23

NCBI Official Symbol

DUSP23

NCBI Official Synonym Symbols

VHZ; MOSP; LDP-3; DUSP25

UniProt Protein Name

Dual specificity protein phosphatase 23

UniProt Synonym Protein Names

Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z

Protein Family

Dual specificity protein phosphatase

UniProt Gene Name

DUSP23

UniProt Synonym Gene Names

LDP3; VHZ; LDP-3

UniProt Entry Name

DUS23_HUMAN

NCBI Protein Information

dual specificity protein phosphatase 23

UniProt Comments for DUSP23

DUSP23: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Protein type: Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis; EC 3.1.3.48; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: cytosol; nucleus

Molecular Function: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity

Research Articles on DUSP23

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with DUSP23 active protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with DUSP23 and Breast Neoplasms
Nervous System Diseases Antibodies	>1 publications with DUSP23 and Nervous System Diseases

Organs/Tissues associated with DUSP23 active protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with DUSP23 and Brain
Blood Antibodies	>1 publications with DUSP23 and Blood
Liver Antibodies	>1 publications with DUSP23 and Liver
Testis Antibodies	>1 publications with DUSP23 and Testis
Placenta Antibodies	>1 publications with DUSP23 and Placenta
Embryonic Tissue Antibodies	>1 publications with DUSP23 and Embryonic Tissue