• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Il-6:fc (IL4) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS636196

Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to… More details

$575 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-6:Fc (IL4), Active Protein
Full Product Name
IL-6, Recombinant, Mouse:Fc (Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1)
Product Gene Name
Sequence
The extracellu lar domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2.
Host
Human, Mouse, HEK 293 cells
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 1 year after receipt when stored at -20 degree C. Working aliquots are stable for up to 3 months when stored at -20 degree C.
Molecular Weight
16,562 Da
Chromosome Location
Chromosome: 3; NC_013671.1 (15702780..15711433). Location: chromosome: 3
3D Structure
ModBase 3D Structure for Q9MZR8
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml.

Other Notes

Small volumes of IL4 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL4 purchase

MBS636196 is an active protein targeting IL4. Also known as IL-6, Recombinant, Mouse:Fc (Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1). Host: Human, Mouse, HEK 293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for IL4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interleukin-4
NCBI Official Symbol
IL4
NCBI Official Synonym Symbols
IL2; BSF-1
UniProt Protein Name
Interleukin-4
UniProt Synonym Protein Names
B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
Protein Family
UniProt Gene Name
IL4
UniProt Synonym Gene Names
IL-4; BSF-1
UniProt Entry Name
IL4_RABIT
NCBI Protein Information
interleukin-4; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1

UniProt Comments for IL4

Function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the IL-4/IL-13 family.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000