MIA Active Protein

Name: MIA Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS844967
Price: 340 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844967

Background: MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MIA, Active Protein

Full Product Name

MIA, human recombinant

Product Gene Name

MIA active protein

Product Synonym Names

Melanoma-derived growth regulatory protein precursor; Cartilage-derived retinoic acid-sensitive protein; CD-RAP; MIA; Melanoma inhibitory activity protein

Host

E Coli

Form/Format

Sterile filtered and lyophilized with no additives
Appearance: Lyophilized protein

Purity/Purification

>=98%

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

12.2 kDa

OMIM

601340

3D Structure

ModBase 3D Structure for Q16674

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility/Reconstitution Instructions

Reconstitute in H?O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers

Endotoxin Level

<0.1 ng/mug

Biological Activity

The biological activity is determined by the inhibitory effect on the invasion of Mel In Tumor cells and found active in Mel In assay.

Handling

Centrifuge the vial prior to opening.

Applications Tested/Suitable for MIA active protein

SDS-PAGE; HPLC

Other Notes

Small volumes of MIA active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIA purchase

MBS844967 is an active protein targeting MIA. Also known as MIA, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MIA. It may not necessarily be applicable to this product.

NCBI GI #

321400133

NCBI GeneID

8190

NCBI Accession #

NP_001189482.1

UniProt Primary Accession #

Q16674

UniProt Secondary Accession #

Q6FHV3

UniProt Related Accession #

Q16674

GenBank Nucleotide #

NM_001202553.1

NCBI Official Full Name

melanoma-derived growth regulatory protein

NCBI Official Synonym Full Names

melanoma inhibitory activity

NCBI Official Symbol

MIA

NCBI Official Synonym Symbols

CD-RAP

UniProt Protein Name

Melanoma-derived growth regulatory protein

UniProt Synonym Protein Names

Melanoma inhibitory activity protein

Protein Family

Melanoma-derived growth regulatory protein

UniProt Gene Name

MIA

UniProt Entry Name

MIA_HUMAN

NCBI Protein Information

melanoma-derived growth regulatory protein

UniProt Comments for MIA

MIA: Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. Belongs to the MIA/OTOR family.

Protein type: Secreted; Cell adhesion; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular space

Molecular Function: growth factor activity

Biological Process: cell proliferation

Research Articles on MIA

1. The effects of MIA/CD-RAP on transcriptional regulation in chondrocytes, through the regulation of p54(nrb) via YBX1 contributes to the understanding of chondrogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.