Trypsin Inhibitor, Corn (LOC541688) Active Protein

Corn Trypsin Inhibitor (CTI) is a small protein that is localized in the kernels of most species of corn. CTI is not only an inhibitor of trypsin, it is also a specific inhibitor of human Factor XIIa when tested in blood clotting experiments (1-6). The inhibitor forms a one-to-one complex with either trypsin or Factor XIIa. When added to plasma, it prolongs the activated partial thromboplastin time without affecting the PT assay (6). The specificity for Factor XIIa makes the inhibitor useful for the segregation and study of coagulation reactions (6).

The protein is a single chain molecule comprised of 112 amino acids (3,7). This yields a calculated molecular weight of 12,028D (7). The calculated molecular weight and that which has been determined by sedimentation equilibrium analyses of the purified protein (12,500D) are in good agreement (3). A comparison of the amino acid sequence of CTI to that of other trypsin or serine protease inhibitors reveals little or no similarities (7).

Small volumes of LOC541688 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS634314 is an active protein targeting LOC541688. Also known as Trypsin Inhibitor, Corn (CTI). Host: Corn kernels.