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ARC Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS194026

Apoptosis is regulated by death domain (DD)- and/or caspase recruitment domain (CARD)-containing molecules and a caspase family of proteases. CARD domain-containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD… More details

$560 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARC (CT), Antibody
Full Product Name
Anti-ARC (CT) Antibody
Product Gene Name
anti-ARC antibody
Product Synonym Names
Anti-ARC (CT); ARC (CT)
Host
Rabbit
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Specificity
Anti-ARC (CT) [Rabbit antibody to peptide corresponding to aa 191-208 at C-terminus of human apoptosis repressor with CARD (ARC).]
This antibody recognizes full-length ARC (25 kD).
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Molecular Weight
45,316 Da
OMIM
612461
3D Structure
ModBase 3D Structure for Q7LC44
Antigen
Peptide corresponding to aa 191-208 of human ARC.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.

Product Categories/Family for anti-ARC antibody

Apoptosis Antibodies
Applications Tested/Suitable for anti-ARC antibody
Immunoblot
Application Notes for anti-ARC antibody
Immunoblotting: use at 1:1,000 dilution.
Positive control: Whole cell lysate of HeLa, KB, and A549 cells.

Other Notes

Small volumes of anti-ARC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARC purchase

MBS194026 is an antibody targeting ARC. Also known as Anti-ARC (CT) Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARC. It may not necessarily be applicable to this product.

NCBI GI #
6319152
NCBI GeneID
23237
NCBI Accession #
AAF07185.1
UniProt Primary Accession #
Q7LC44
UniProt Secondary Accession #
Q9UJW6; Q9Y469
UniProt Related Accession #
Q7LC44
NCBI Official Full Name
ARC
NCBI Official Synonym Full Names
activity-regulated cytoskeleton-associated protein
NCBI Official Symbol
ARC
NCBI Official Synonym Symbols
Arg3.1; KIAA0278; ARC
UniProt Protein Name
Activity-regulated cytoskeleton-associated protein
UniProt Synonym Protein Names
ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog
Protein Family
AAA ATPase forming ring-shaped complexes
UniProt Gene Name
ARC
UniProt Synonym Gene Names
KIAA0278
UniProt Entry Name
ARC_HUMAN
NCBI Protein Information
activity-regulated cytoskeleton-associated protein

UniProt Comments for ARC

ARG3.1: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Belongs to the ARC/ARG3.1 family.

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; dendritic spine; acrosome; plasma membrane; cell junction; endosome; actin cytoskeleton

Biological Process: anterior/posterior pattern formation; cell migration; regulation of cell morphogenesis; cytoskeleton organization and biogenesis; endocytosis; learning; endoderm development; regulation of neuronal synaptic plasticity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ARC antibody

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Diseases associated with anti-ARC antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >637 publications with ARC and Pain
 Mental Disorders Antibodies  >338 publications with ARC and Mental Disorders
 Lung Diseases Antibodies  >324 publications with ARC and Lung Diseases
 Obesity Antibodies  >216 publications with ARC and Obesity
 Genetic Diseases, Inborn Antibodies  >194 publications with ARC and Genetic Diseases, Inborn
 Genital Diseases, Male Antibodies  >183 publications with ARC and Genital Diseases, Male
 Inflammation Antibodies  >162 publications with ARC and Inflammation
 Weight Loss Antibodies  >124 publications with ARC and Weight Loss
 Prostatic Diseases Antibodies  >123 publications with ARC and Prostatic Diseases
 Kidney Diseases Antibodies  >110 publications with ARC and Kidney Diseases

Organs/Tissues associated with anti-ARC antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2293 publications with ARC and Brain
 Blood Antibodies  >2245 publications with ARC and Blood
 Bone Antibodies  >1237 publications with ARC and Bone
 Eye Antibodies  >1087 publications with ARC and Eye
 Lung Antibodies  >387 publications with ARC and Lung
 Liver Antibodies  >182 publications with ARC and Liver
 Prostate Antibodies  >156 publications with ARC and Prostate
 Adrenal Gland Antibodies  >38 publications with ARC and Adrenal Gland
 Placenta Antibodies  >15 publications with ARC and Placenta
 Uncharacterized Tissue Antibodies  >3 publications with ARC and Uncharacterized Tissue
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