Bim (in) Antibody – Rabbit

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain, and BH3 domain-containing pro-apoptotic proteins (such as Bad, Bax, Bid, Bik, and Hrk) form a growing subclass of the Bcl-2 family. A novel BH3 domain-containing protein was recently identified and designated Bim or BOD from human, mouse, and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 subfamily including Bcl-2, Bcl-xL, and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

Small volumes of anti-Bim (IN) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS194036 is an antibody targeting Bim (IN). Host: Rabbit.