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Ac2-12 TFA

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5824860

Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibits neutrophil extravasation and demonstrates antimigratory effects by attenuating the recruitment of neutrophils in experimental models of inflammation. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ac2-12, Biochemical
Full Product Name
Ac2-12 TFA
Product Gene Name
Ac2-12 biochemical
Preparation and Storage
Powder: -20 degree C for 3 years | In solvent: -80 degree C for 1 year
Solubility
(< 1 mg/ml refers to the product slightly soluble or insoluble)
In_vitro
Ac2-12 TFA, administered intravenously at a dosage of 6.7 mg/kg (approximately 70 nmol per mouse), emulates the effects of lipocortin 1 (LC1) and Ac2-26 in male Swiss Albino mice weighing 10-15 grams [1]. Furthermore, a 100 ug dose notably diminishes polymorphonuclear leukocyte (PMN) infiltration in C57BL/6 wild-type mice, while it lacks efficacy in FPR knockout (KO) mice [2].

Other Notes

Small volumes of Ac2-12 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ac2-12 purchase

MBS5824860 is a biochemical targeting Ac2-12. Also known as Ac2-12 TFA.
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